Results 51 to 60 of about 3,494,114 (284)

Investigation of heat transfer augmentation through use of internally finned and roughened tubes : final summary report [PDF]

open access: yes, 1970
This report summarizes a three-year program concerned with obtaining basic design information for tubes having a random roughness on the inside wall (RID) and tubing having continuous internal fins (Forge Fin).
Brown, G. S.   +4 more
core  

High Reynold Number LES of a Rotating Two-Pass Ribbed Duct

open access: yesAerospace, 2018
Cooling of gas turbine blades is critical to long term durability. Accurate prediction of blade metal temperature is a key component in the design of the cooling system.
Danesh Tafti, Cody Dowd, Xiaoming Tan
doaj   +1 more source

A review of drag reduction and heat transfer enhancement by riblet surfaces in closed and open channel flow

open access: yesInternational Journal of Thermofluids, 2021
Turbulence and heat transfer are two critical factors in the chain of world energy consumption. Hence, development of more efficient energy transfer techniques in engineering applications through control and optimization of the thermal turbulent boundary
Shima Soleimani, Steven Eckels
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

The influence of return bends on the downstream pressure drop and condensation heat transfer in tubes [PDF]

open access: yes, 1971
The influence of return bends on the downstream pressure drop and heat transfer coefficient of condensing refrigerant R-12 was studied experimentally. Flow patterns in glass return bends of 1/2 to 1 in. radius and 0.315 in. I. D.
Traviss, Donald P., Rohsenow, Warren M.
core  

Heat Transfer Enhancement in a Duct with Two Right Angled Bends [PDF]

open access: yesEngineering and Technology Journal, 2010
A numerical study was carried out to predict the behavior of complex flow and forced convection heat transfer characteristics in a duct with two right. angled bends for both laminar and turbulent flows. The finite differences method was employed to solve
Jalal M. Jalil   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Implementation of algebraic turbulent heat flux into Reynolds stress transport model and simulation of crossing tube bundles

open access: yesNuclear Engineering and Technology
Lead bismuth eutectic (LBE) is an excellent coolant for fast reactors, owing to its high boiling point and high thermal conductivity. Turbulent heat transfer is a complex phenomenon, and the numerical heat transfer of LBE is constrained by its extremely ...
Han Liu   +4 more
doaj   +1 more source

Numerical investigation of turbulent mixed convection flow and heat transfer characteristics of 2 × 2 subchannels with spacer grids

open access: yesEnergy Science & Engineering, 2023
In turbulent mixed convection conditions, flow and heat transfer can deteriorate under specific conditions, thus affecting the performance of the safety of the system, which could imperil the safety of the nuclear reactor. In this paper, by analyzing the
Jianping Long   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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