Results 121 to 130 of about 5,421,281 (277)

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

Environmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten, Jan van Benthem, Takeshi Morita, Raffaella Corvi, Patricia A. Escobar, Yurika Fujita, Jennifer Hemmerich, Naveed Honarvar, David Kirkland, Naoki Koyama, David P. Lovell, Miriam Mathea, Andrew Williams, Stephen Dertinger, Stefan Pfuhler, Jeroen L. A. Pennings   +15 more
wiley   +1 more source

Do Institutions Make Street‐Level Bureaucrats Prosocial? Agent‐Based Evidence Shows That New Public Management Does Not

European Policy Analysis, EarlyView.
ABSTRACT Does street‐level bureaucrats' (SLBs) willingness to sacrifice their own self‐interests to meet the needs of their clients vary depending on their contexts? To date, it has been very challenging to empirically examine how SLBs who have different orientations toward social values might act in different institutional and administrative contexts.
Nissim Cohen, Teddy Lazebnik
wiley   +1 more source

Pattern formation of a Schnakenberg-type plant root hair initiation model

Electronic Journal of Qualitative Theory of Differential Equations, 2018
This paper concentrates on the diversity of patterns in a quite general Schnakenberg-type model. We discuss existence and nonexistence of nonconstant positive steady state solutions as well as their bounds.
Yanqiu Li, Juncheng Jiang
doaj   +1 more source

Work Has Changed, Has HRM? Designing for the Distributed, Fragmented, and Fluid Era

Human Resource Management, EarlyView.
ABSTRACT This paper addresses the growing misalignment between traditional human resource management (HRM) systems and the realities of distributed, fluid, and fragmented work. To address this issue, we introduce the FLUID‐HRM framework—a layered design architecture that reconfigures core HRM domains (resourcing, rewards, development, relations, work ...
Černe Matej, Lamovšek Amadeja
wiley   +1 more source

Comparison of Auto‐Contouring Tools for Delineation of Normal Organs at Risk in Paediatric Patients Undergoing Radiotherapy

Journal of Medical Radiation Sciences, EarlyView.
Contouring organs at risk (OARs) manually in paediatric patients undergoing cranial‐spinal radiation therapy (CSI) is a time‐consuming, labour‐intensive task. This study aims to assess the accuracy and clinical acceptability of auto‐contours produced by the Siemens DirectORGANS auto‐contouring software on paediatric patients receiving CSI treatment ...
Isabel Cant, Jonathan Sykes, Yolanda Surjan, Rachael Beldham‐Collins, Laura Murphy, John Fernandez, Alison Salkeld   +6 more
wiley   +1 more source

Theory of Turing pattern formation and its experimental realization in the CIMA reaction system in the presence of materials lowering the diffusivity of activators

Frontiers in Physics
In 1952, Alan Turing accomplished a pioneering theoretical study to show that the coupling of nonlinear chemical reactions and diffusion leads to the instability of spatially homogeneous states.
Amiko Aizawa, Kouichi Asakura
doaj   +1 more source

Should Dermatologists Recommend Direct‐to‐Consumer App‐Based Remote Diagnostics? An Ethical Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Dermatology patients still face barriers in accessing timely specialist care. As direct‐to‐consumer (DTC) apps for remote dermatological diagnostics proliferate, guidance is lacking. While promising efficiency and efficacy, their clinical—and ethical—legitimacy is not yet well established.
Sonja Mathes, Sebastian Seurig, Theresa Willem, Marta Dechant, Stephan Traidl, Mina Kang, Pedro Marques Pinto, Annette Binder, Tilo Biedermann, Ulf Darsow   +9 more
wiley   +1 more source

Optimal Control and Spatial Heterogeneity: Pattern Formation in Economic-Ecological Models [PDF]

This paper extends Turing analysis to standard recursive optimal control frameworks in economics and applies it to dynamic bioeconomic problems where the interaction of coupled economic and ecological dynamics under optimal control over space creates (or
Anastasios Xepapadeas, William Brock
core  

Instabilities and Patterns in Coupled Reaction-Diffusion Layers

, 2012
We study instabilities and pattern formation in reaction-diffusion layers that are diffusively coupled. For two-layer systems of identical two-component reactions, we analyze the stability of homogeneous steady states by exploiting the block symmetric ...
Catlla, Anne J., McNamara, Amelia, Topaz, Chad M.   +2 more
core   +1 more source

Consumer‐Perceived Responsible Innovation: Scale Development and Its Influence on Adoption and Anticonsumption

Psychology &Marketing, EarlyView.
ABSTRACT Responsible innovation (RI) seeks to align innovation processes with societal values and ethical principles. Understanding how consumers perceive RI is crucial, as innovation failures often arise from mismatches between managerial intentions and consumer expectations.
Stefan Hoffmann, Christina Jobst, Kristina Nickel, Susanne C. Liebermann, Carsten Schultz   +4 more
wiley   +1 more source