Results 91 to 100 of about 7,470 (228)

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Emergence of Diverse Epidermal Patterns via the Integration of the Turing Pattern Model with the Majority Voting Model

open access: yesBiophysica
Animal skin patterns are increasingly explained using the Turing pattern model proposed by Alan Turing. The Turing model, a self-organizing model, can produce spotted or striped patterns.
Takeshi Ishida
doaj   +1 more source

Modeling n‐Butyl Acrylate Polymerization using Complementary Modeling Techniques

open access: yesMacromolecular Reaction Engineering, EarlyView.
Two different simulation methods are used for the radical polymerization of nBA: deterministic in Predici and stochastic with mcPolymer. It has been successfully implemented across a wide temperature range. It turns out that the partially different implementation of chain‐length‐dependent termination and β‐scission are important for obtaining ...
Marco Drache   +3 more
wiley   +1 more source

Combined CFD and Monte Carlo Simulation for Modeling the Impact of Mixing on the High‐Pressure Polymerization of Ethylene

open access: yesMacromolecular Reaction Engineering, EarlyView.
This article addresses the impact of mixing on polymer properties during high‐pressure polymerization of ethylene. Mixing is analyzed using CFD simulations, including polymerization kinetics. Detailed polymer properties are obtained through Monte Carlo simulations. Both modeling steps are linked via a compartmentalization approach.
Lena Gockel, Emil Schwarz, Markus Busch
wiley   +1 more source

Pattern Dynamics in a Spatial Predator-Prey System with Allee Effect

open access: yesAbstract and Applied Analysis, 2013
We investigate the spatial dynamics of a predator-prey system with Allee effect. By using bifurcation analysis, the exact Turing domain is found in the parameters space.
Gui-Quan Sun   +4 more
doaj   +1 more source

Spatiotemporal Patterns Formed by a Discrete Nutrient-Phytoplankton Model with Time Delay

open access: yesComplexity, 2020
In this research, a continuous nutrient-phytoplankton model with time delay and Michaelis–Menten functional response is discretized to a spatiotemporal discrete model.
Feifan Zhang   +4 more
doaj   +1 more source

Environmental Stressors Influence Spatial Complexity in a Fluvial Macrophyte meadow

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
This research investigates the nonlinear relationships between environmental stressors and the fine‐scale spatial complexity of a fluvial macrophytes meadow. The use of multivariate spatial analysis allowed us to identify two major environmental gradients (nutrients and light) and two major complexity gradients (related to abundance and fragmentation).
Arthur de Grandpré   +2 more
wiley   +1 more source

Generative AI—the Transgression of Technology

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT This article offers a systems‐theoretical analysis of generative artificial intelligence (GenAI) grounded in Niklas Luhmann's sociology of technology. It addresses a central conceptual problem: How GenAI can be understood within a theoretical framework that has traditionally defined technology as a means of stabilising action through causal ...
Jesper Tække
wiley   +1 more source

Density-dependent effects on Turing patterns and steady state bifurcation in a Beddington–DeAngelis-type predator–prey model

open access: yesBoundary Value Problems, 2019
In this paper, Turing patterns and steady state bifurcation of a diffusive Beddington–DeAngelis-type predator–prey model with density-dependent death rate for the predator are considered.
Hongwu Xu, Shengmao Fu
doaj   +1 more source

An Innovative Approach to Multi‐Valued Logic

open access: yesIEEJ Transactions on Electrical and Electronic Engineering, EarlyView.
The current generation of computer systems operates on the principles of binary logic, which encompasses both logical and arithmetic operations. However, silicon technology has reached its peak performance, prompting researchers to explore alternative methods for enhancing computational efficiency. One such method is the adoption of Multi‐Valued Logic (
Ali Mokhtari, Peyman Kabiri
wiley   +1 more source

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