Results 121 to 130 of about 566,879 (312)

Around the table: Are multiple-touch surfaces better than single-touch for children's collaborative interactions? [PDF]

open access: yes, 2009
This paper presents a classroom study that investigated the potential of using touch tabletop technology to support children's collaborative learning interactions.
Bonnett, Victoria   +6 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

open access: yesFEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey   +2 more
wiley   +1 more source

Pragmatic functions of lengthenings and filled pauses in the adult-directed speech of Hungarian children [PDF]

open access: yes, 2013
Two most common disfluencies of spontaneous speech, vowel lengthenings (VLE) and non-lexicalized filled pauses (NLFP) were investigated in the adult-directed speech of eight Hungarian children.
Deme, Andrea
core  

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma   +5 more
wiley   +1 more source

The role of answer content and length when preparing answers to questions

open access: yesScientific Reports
Research suggests that interlocutors manage the timing demands of conversation by preparing what they want to say early. In three experiments, we used a verbal question-answering task to investigate what aspects of their response speakers prepare early ...
Ruth Elizabeth Corps   +1 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Interruptions Employed by the Participants of Ellen DeGeneres Show

open access: yesJournal of English Education and Teaching
This research aimed to find out the dominant types of interruptions employed by participants and to find out the purposes of interruptions done by the participants of Ellen DeGeneres show. This research employed quantitative descriptive research.
Astri Amaliah Fatonah   +2 more
doaj   +1 more source

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