Results 41 to 50 of about 552,176 (210)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Analyzing classroom interactions focusing on IRF patterns and turn-taking
English Learning InnovationThis study aims to analyze patterns of interaction and turn-taking in the context of classroom learning using a classroom discourse analysis approach.
Efendi Hidayatullah
doaj +1 more source
Experience sharing, emotional reciprocity, and turn-taking
Frontiers in Psychology, 2015 In this perspective article, we consider the relationship between experience sharing and turn-taking. There is much evidence suggesting that human social interaction is permeated by two temporal organizations: (1) the sequential framework of turn-taking ...
Melisa eStevanovic, Anssi ePeräkylä
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Conditional Cooperation and Turn-Taking in Parental Care
Frontiers in Ecology and Evolution, 2019 Sexual conflict is inescapable when two parents care for offspring, because providing care is personally costly, while the benefits of successful reproduction are shared.
Rufus A. Johnstone +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
ORGANISATION AND ALLOCATION OF TURNS AT THE OPUTA PANEL SESSIONS
Journal of Central and Eastern European African StudiesThis study investigates the turn-taking sequence, organisation of turns and the question patterns adopted during the examination of witnesses at the Oputa Panel sessions.
Oluwakemi Olayemi
doaj +1 more source
Classroom interaction: Turn-taking as a pedagogical strategy
Per Linguam : A Journal of Language Learning, 2010 This paper reports on findings of a case study which analysed classroom interaction through turn-taking in Grade 4 science lessons taught through the medium of a home language and an additional language.
Nomlomo,Vuyokazi
doaj +1 more source