Results 101 to 110 of about 2,629,242 (377)
European Integration – Democracy Promotion by the EU in Eastern Europe [PDF]
, 2007 There have been a few historical turning points in modern European history. The turning points of 1648, 1815, 1919 and 1945 had great impact on the developments of Europe. The last turning point of 1991 is not an exception to such record. The collapse
Silander, Daniel
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
High Prescribing: A Case Study of High-Potency Medicinal Cannabis Inducing Psychosis
Case Reports in PsychiatryConclusion: There are clear dangers to overprescribing medicinal cannabis and the care that needs to be taken by prescribers to avoid them. There is a need for a change in the regulation of cannabis prescribing in Australia. Further research is warranted
Richard C. J. Bradlow +3 more
doaj +1 more source
Most recent risky drinking session with Australian teenagers
Australian and New Zealand Journal of Public Health, 2017 Objective: Despite declines in Australian alcohol consumption, youth alcohol related harms remain prevalent. These alcohol‐related consequences appear to be driven by a subset of risky drinkers who engage in ‘high intensity’ drinking episodes and are ...
Tina Lam +11 more
doaj +1 more source
Theoretical Inquiries in Law, 2019 The problem of theorizing privacy moves on two levels, the first consisting of an inadequate conceptual vocabulary and the second consisting of an inadequate institutional grammar.
Julie E. Cohen
semanticscholar +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Frontiers in Neurology, 2019 Introduction: Mobility declines with age and further with neurodegenerative disorders, such as Parkinson's disease (PD). Walking and turning ability, in particular, are vital aspects of mobility that deteriorate with age and are further impaired in PD ...
S. Stuart +3 more
semanticscholar +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source