Results 151 to 160 of about 147,625 (308)

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

18th Century Turning Points in U.S. History: 1767-1776

open access: yes, 2008
1766 John Singleton Copley Paints "Boy with the Squirrel"1767 Daniel Boone Views Kentucky1768 Indiana Co. buys 1,800,000 acres from the Iroquois1770 The Liberty Pole Riot and the Boston Massacre1773 The Boston Tea Party1774 The First Continental Congress

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CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

19th Century Turning Points in U.S. History: 1846-1860

open access: yes, 2008
1846 ? DR.MORTON DEMONSTRATES PAINLESS SURGERY USING ETHER1848 ? GOLD IS DISCOVERED AT SUTTER?S MILL1849 ? TREATY BETWEEN U.S. AND HAWAIIAN ISLANDS1852 ? HARRIET BEECHER STOWE PUBLISHES ?UNCLE TOM?S CABIN?1854 ?

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Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

19th Century Turning Points in U.S. History: 1866-1870

open access: yes, 2008
1867 ? CARPETBAGGERS DESCEND ON THE SOUTH1867 ? U.S. ACQUIRES ALASKA? SEWARD?S FOLLY1868 ? PRESIDENT JOHNSON IS IMPEACHED1869 ? COMPLETION OF THE TRANS CONTINENTAL RAILROAD1870 ? ROCKEFELLER INCORPORATES STANDARD OIL CO.

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Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

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