Results 141 to 150 of about 2,570,686 (307)

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

18th Century Turning Points in U.S. History: 1767-1776

open access: yes, 2008
1766 John Singleton Copley Paints "Boy with the Squirrel"1767 Daniel Boone Views Kentucky1768 Indiana Co. buys 1,800,000 acres from the Iroquois1770 The Liberty Pole Riot and the Boston Massacre1773 The Boston Tea Party1774 The First Continental Congress

core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

I turning points sociologici dell’identità

open access: yesSocietàMutamentoPolitica: Rivista Italiana di Sociologia, 2013
Gianfranco Bettin Lattes
doaj   +1 more source

Age-Graded Transitions and Turning Points in Polish Offenders' Criminal Careers from the Standpoint of Life Course Theory. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Pękala K   +8 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Bifurcation for an elliptic problem with nonlinear boundary conditions

open access: yesRevista Integración, 2012
This paper gives a survey over bifurcation problems for elliptic equations with nonlinear boundary conditions depending on a real parameter. We consider an elliptic equation with a nonlinear boundary condition which is asymptotically linear at ...
Rosa Pardo
doaj  

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