Results 131 to 140 of about 147,625 (308)

Olfaction in patients with Parkinson's disease: a new threshold test analysis through turning points trajectories. [PDF]

open access: yesJ Neural Transm (Vienna), 2021
Cecchini MP   +7 more
europepmc   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

18th Century Turning Points in U.S. History: 1700-1713

open access: yes, 2008
1701 The English Board of Trade Creates Royal Colonies1701 The French Return Soldiers to the North American Interior1701 Yale College is Founded1702 Colonists Sack St Augustine1702 Cotton Mather publishes "The Ecclesiastical History of New England."1709 ...

core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

18th Century Turning Points in U.S. History: 1791-1799

open access: yes, 2008
1792 Benjamin Banneker Saves the White House1793 Congress Enacts a Fugitive Slave Law1794 The Whiskey Rebellion is Put Down1794 & 1795 The Jay and Pinckney Treaties Protect America's Westward Expansion1796 John Adams Becomes the Second President of ...

core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School. [PDF]

open access: yesJ Autism Dev Disord, 2022
Georgiades S   +16 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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