Using time-dependent reproduction number to predict turning points of COVID-19 outbreak in Dalian, Liaoning province, China. [PDF]
BMC Infect Dis, 2022 An Q, Wu J, Bai JJ, Li X.
europepmc +1 more source
Using the Dynamic Bi-Factor Model with Markov Switching to Predict the Cyclical Turns in the Large European Economies [PDF]
The appropriately selected leading indicators can substantially improve the forecasting of the peaks and troughs of the business cycle. Using the novel methodology of the dynamic bi-factor model with Markov switching and the data for three largest ...
Konstantin A. Kholodilin
core
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Turning points in the history of Nordic higher education
Kasvatus & Aika, 2009 An editorial written by visiting editor Pieter ...
Pieter Dhondt
doaj +2 more sources
"I'm Glad that I was Given a Second Chance to Live": The Buffering Impact of Turning Points in the Lives of Young People with Foster Care Experience. [PDF]
Int J Child Maltreat, 2023 Taussig HN +3 more
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Temps longs et temps courts dans les parcours de jeunes adultes en situation de précarité
Sociétés et Jeunesses en Difficulté, 2018 The decline of a homogenous social time in industrial societies opens up the way to a pluralization of social temporalities. A process recognizable in young adults’ life courses regarding the density of transitions encountered during their process to ...
Eddy Supeno, Sylvain Bourdon
doaj
Insights into turning points from the perspective of young people with out-of-home care experience: events, impact and facilitators of change. [PDF]
Dev Child Welf, 2022 Roberts L, Scourfield J, Taussig H.
europepmc +1 more source
19th Century Turning Points in U.S. History: 1814-1826
, 2008 1814 ? WASHINGTON DC IS CAPTURED AND BURNED BY THE BRITISH1814 ? STAR SPANGLED BANNER IS WRITTEN1815 ? BATTLE OF NEW ORLEANS1819 ? WASHINGTON IRVING PUBLISHES ?RIP VAN WINKLE?1821 ? INAUGURATION OF THE SANTA FE TRAIL1825 ?
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source