Results 111 to 120 of about 147,625 (308)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Investigation of turning points in the effectiveness of Covid-19 social distancing. [PDF]

Sci Rep, 2022
Neuwirth C, Gruber C.
europepmc   +1 more source

18th Century Turning Points in U.S. History: 1736-1750

, 2008
1739 The Great Awakening Begins1739 Black Uprising in South Carolina1739 The War of Jenkins Ear Begins1739-41 New Explorations1747 The Ohio Land Company is Established1750 Native American Horse Cultures Dominate the Great Plains1750 Parliament Passes ...

core  

Turning-Point

, 2015
The list of turning points in coexpression ...
Okamura, Yasunobu, Yasunobu Okamura (766304), Kinoshita, Kengo, Obayashi, Takeshi, Takeshi Obayashi (308624), Kengo Kinoshita (13965)   +5 more
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Bibliometric insights in fournier's gangrene: Research landscapes, turning points, and global trends. [PDF]

Front Surg, 2023
Zhang JY, Xiao CF, Wang C, Yao YB.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Turning points [PDF]

Nature Cell Biology, 2009
openaire   +2 more sources

Turning Points: [PDF]

J Spinal Cord Med, 2008
openaire   +2 more sources

Using time-dependent reproduction number to predict turning points of COVID-19 outbreak in Dalian, Liaoning province, China. [PDF]

BMC Infect Dis, 2022
An Q, Wu J, Bai JJ, Li X.
europepmc   +1 more source