Results 81 to 90 of about 4,517,907 (325)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Dating Business Cycle Turning Points [PDF]

open access: yes
This paper discusses formal quantitative algorithms that can be used to identify business cycle turning points. An intuitive, graphical derivation of these algorithms is presented along with a description of how they can be implemented making very ...
James D. Hamilton, Marcelle Chauvet
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Development tendencies and turning points of futures studies

open access: yesEuropean Journal of Futures Research
In honor of its 50th anniversary, the World Futures Studies Federation (WFSF) held its XXV World Conference in Paris. The conference provided a venue for reviewing earlier developments and reevaluating prospective directions in the futures field ...
Tamás Kristóf
doaj   +1 more source

Turning points identification of growth business cycle in the Czech republic – an alternative approach

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
The purpose of the paper is to identify GDP growth cycle of the Czech Republic by means of turning points identification using alternative statistical method – non-parametric kernel estimate.
Jitka Poměnková
doaj   +1 more source

Finding turning‐points in ultra‐high‐resolution animal movement data

open access: yesMethods in Ecology and Evolution, 2018
Recent advances in biologging have resulted in animal location data at unprecedentedly high temporal resolutions, sometimes many times per second. However, many current methods for analysing animal movement (e.g.
Jonathan R. Potts   +5 more
semanticscholar   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Business confidence and cyclical turning points: A Markov-Switching approach [PDF]

open access: yes, 2007
Markov regime-switching analysis is used to consider the relationship between business confidence and the probability of turning points in cyclical GDP.
Holmes, Mark J., Silverstone, Brian
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A turning point analysis of the ergodic dynamics of iterative maps

open access: yes, 1997
The dynamics of one dimensional iterative maps in the regime of fully developed chaos is studied in detail. Motivated by the observation of dynamical structures around the unstable fixed point we introduce the geometrical concept of a turning point which
Diakonos, F. K., Schmelcher, P.
core   +1 more source

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