RAB5A Promotes Active Fluid Wetting by Reprogramming Breast Cancer Spheroid Mechanics
RAB5A‐mediated unjamming enhances active wetting through distinct biomechanical processes: a) upregulation of specific integrin subunits, enhanced focal adhesions kinetics and activity; b) supracellular organization relying on nanoscale integrin clustering, and the formation of a stiff and collective actin cable; and c) softening of the spheroid core ...
Grégoire Lemahieu+19 more
wiley +1 more source
Exploring the reasons and significant influencing factors of serious turnover intentions among nurses in Saudi Arabia. [PDF]
Saleh ZT+10 more
europepmc +1 more source
STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan+10 more
wiley +1 more source
Unraveling the drivers of forage quality variation in the Serengeti. [PDF]
Li Y+5 more
europepmc +1 more source
The CuW nanoalloy is synthesized via electrodeposition, with the coexistence of Cu, W/WO3 enhancing hydrogen spillover and improving hydrogen oxidation. W/WO3 facilitates hydrogen adsorption, whereas Cu supports hydrogen spillover and oxidation catalysis.
Bingyan Xiong, Lisong Chen, Jianlin Shi
wiley +1 more source
Carrot and stick: how RNase R contributes to function and destruction of the translation machinery. [PDF]
Paternoga H, Dimitrova-Paternoga L.
europepmc +1 more source
Cu7S4 nanozymes, exhibiting peroxidase‐like, catalase‐like, and GSH‐depletion activities, are synthesized through defect engineering. These nanozymes demonstrate rapid inactivation of Gram‐negative bacteria, including Escherichia coli and Pseudomonas aeruginosa. In a mouse skin wound model infected with P. aeruginosa, the nanozyme showcases exceptional
Xueya Li+15 more
wiley +1 more source
Community Pharmacy Turnover and Context of Openings and Closings by Ownership Type.
Mattingly TJ, Sahu M, Anderson KE.
europepmc +1 more source
Trends in turnover and turbulence at a large academic medical center before and during COVID-19: Analyzing structured clinical research professional roles. [PDF]
Stroo M+6 more
europepmc +1 more source
How emotional labor leads to turnover intention: the mediating role of job burnout and the moderating role of social support among rural physical education teachers in China. [PDF]
Sun P+5 more
europepmc +1 more source