Results 71 to 80 of about 2,457,689 (293)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

UPAYA PENINGKATAN KELARUTAN HIDROKLORTIAZIDA DENGAN PENAMBAHAN SURFAKTAN TWEEN 80 [PDF]

, 2007
Salah satu sifat fisikokimia terpenting dari suatu obat yang menentukan absorbsinya adalah kelarutan yang pada akhirnya menentukan efek terapeutik dari bahan obat tersebut.
KRISTIANTI, YUNI
core   +1 more source

Stability studies of silymarin nanoemulsion containing Tween 80 as a surfactant

Journal of Pharmacy and Bioallied Sciences, 2015
Background: Silymarin, a flavonolignan from "milk thistle" (Silybum marianum) plant is used almost exclusively for hepatoprotection. Because of its low bioavailability, it was incorporated into a nanoemulsion formulation. The aim of the present study was
Rabea Parveen, Sanjula Baboota, Javed Ali, Alka Ahuja, Sayeed Ahmad   +4 more
doaj   +1 more source

A novel paclitaxel-loaded poly(D,L-lactide-co-glycolide)-Tween 80 copolymer nanoparticle overcoming multidrug resistance for lung cancer treatment

, 2016
Xun Yuan,1,* Wenxiang Ji,2,* Si Chen,1 Yuling Bao,3 Songwei Tan,3 Shun Lu,2 Kongming Wu,1 Qian Chu11Department of Oncology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 2Lung Tumor Clinical Medical ...
Wu K, Chu Q, Ji W, Bao Y, Lu S, Tan S, Yuan X, Chen S   +7 more
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Preparation of Tween 80-Zn/Al-Levodopa-Layered Double Hydroxides Nanocomposite for Drug Delivery System

The Scientific World Journal, 2014
We incorporated anti-Parkinsonian drug, levodopa (dopa), in Zn/Al-LDH by coprecipitation method to form dopa-LDH nanocomposite. Further coating of Tween-80 on the external surfaces of dopa-LDH nanocomposite was achieved through the oxygen of C=O group of
Aminu Umar Kura, Samer Hasan Hussein-Al-Ali, Mohd Zobir Hussein, Sharida Fakurazi   +3 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Pembuatan Serbuk Buah Jeruk Dengan Metode Pengeringan Busa

Reaktor, 2017
Salah satu produk olahan buahjeruk segar adalah serbuk sari jeruk instan yang dapat diperoleh dengan metode pengeringan busa. Minyak kelapa, dekstri dan tween 80 merupakan bahan aditif yang biasa ditambahkan pada pengeringan usa.
S. Prasetyo
doaj   +1 more source

Bacteria and fungi mediated degradation of poly aromatic hydrocarbons and effect of surfactant Tween-80

, 2021
Microorganisms (17 bacteria and 3 fungi) isolated from crude oil-contaminated soils were evaluated for degradation of five polyaromatic hydrocarbons (PAHs), both in the absence (-T80) and the presence of surfactant Tween-80 (+T80) at a 10 mg L−1 ...
Eldho Varghese (739539), Neera Singh (8135022), Ashish Khandelwal (11857224), Shashi Bala Singh (9362197), Anamika Sharma (4388848), Lata Nain (682732), Suman Gupta (551550)   +6 more
core   +1 more source