Results 41 to 50 of about 707,337 (64)

Conceptual framework for model-based analysis of residence time distribution in twin-screw granulation

, 2015
Twin-screw granulation is a promising continuous alternative for traditional batchwise wet granulation processes. The twin-screw granulator (TSG) screws consist of transport and kneading element modules.
Remon, Jean Paul, Gernaey, Krist V, De Beer, Thomas, Vervaet, Chris, Nopens, Ingmar, Panouillot, Pierre-Emmanuel, Vercruysse, Jurgen, Juuti, Mikko, Kumar, Ashish, Vanhoorne, Valerie, Toiviainen, Maunu, Gernaey, Krist   +11 more
core   +1 more source

Comparison of granule properties produced using Twin Screw Extruder and High Shear Mixer:A step towards understanding the mechanism of twin screw wet granulation

, 2013
The wet granulation process plays an important role in the pharmaceutical industry. With the introduction of a Twin Screw Extruder (TSE), it allows the possibility of wet granulation to be run continuously in contrast to a conventional batch process ...
Ingram, Andy, Rowson, Neil A., Lee, Kai T.   +2 more
core   +1 more source

Twin-screw granulation – a systematic analysis of process parameters [PDF]

Twin-screw granulation has a significant advantage over traditional granulation methods leading to the possibility of continuous manufacturing. Although this technology has drawn attention in recent years, the general understanding of the process is ...
Richter, Margarethe, Kaialy, Waseem, Bello, Hussaini   +2 more
core   +1 more source

Predicting Pharmaceutical Particle Size Distributions Using Kernel Mean Embedding. [PDF]

Pharmaceutics, 2020
Van Hauwermeiren D, Stock M, De Beer T, Nopens I.   +3 more
europepmc   +1 more source

Emerging Technologies in Granulation: Process Analytical Technologies and Modeling Approaches in Pharmaceutical Development and Manufacturing. [PDF]

Pharmaceutics
Pentsis P, Chountoulesi M, Christodoulou E, Pippa N.   +3 more
europepmc   +1 more source

Characterizing a design space for a twin-screw wet granulation process: A case study of extended-release tablets. [PDF]

Int J Pharm
Sierra-Vega NO, Alsharif FM, O'Connor T, Ashraf M, Zidan A.   +4 more
europepmc   +1 more source

Development and evaluation of a continuous granulation technique using a twin-screw extruder

, 2009
The term granulation refers to a process of size-enlargement, whereby primary powder particles are gathered into larger, semi-permanent aggregates (granules) in which the original particles still can be identified. The main reasons for granulation in the
Van Melkebeke, Barbara
core  

Studying the API Distribution of Controlled Release Formulations Produced via Continuous Twin-Screw Wet Granulation: Influence of Matrix Former, Filler and Process Parameters. [PDF]

Pharmaceutics
Denduyver P, Vervaet C, Vanhoorne V.
europepmc   +1 more source

A Formulation-Process-Product Integrated Design Method for Accelerating Pharmaceutical Tablet Development via the High-Shear Wet Granulation and Tableting Route. [PDF]

Pharmaceutics
Liang Z, Tang X, Chen L, Liu Y, Zhao S, Ma X, Luo G, Xu B.   +7 more
europepmc   +1 more source

Evaluation of the Influence of Material Properties and Process Parameters on Granule Porosity in Twin-Screw Wet Granulation

International Journal of Pharmaceutics, 2023
In recent years, continuous twin-screw wet granulation (TSWG) is gaining increasing interest from the pharmaceutical industry. Despite the many publications on TSWG, only a limited number of studies focused on granule porosity, which was found to be an ...
Thomas de Beer, Ingmar Nopens, Fanny Stauffer   +2 more
exaly   +2 more sources