Results 31 to 40 of about 707,337 (64)

Solid–liquid transport in a modified co-rotating twin-screw extruder-dynamic simulator and experimental validations [PDF]

, 2004
This work presents a dynamic transport model of a solid–liquid media through a twin-screw extruder (TSE). The application under consideration is the solid–liquid extraction of solute from raw plant substrate.
Prat, Laurent E., N'diaye, Senghane, Prat, Laurent, Gourdon, Christophe, Rigal, Luc   +4 more
core   +1 more source

TPLS as predictive platform for twin-screw wet granulation process and formulation development

, 2021
In recent years, the interest in continuous manufacturing techniques, such as twin-screw wet granulation, has increased. However, the understanding of the influence of the combination of raw material properties and process settings upon the granule ...
Ryckaert, Alexander, Djuric, Dejan, Funke, Adrian, De Beer, Thomas, Vervaet, Chris, Nopens, Ingmar, Dhondt, Jens, De Man, Alexander, Van Hauwermeiren, Daan, D. Van Hauwermeiren, T. De Beer, A. De Man, A. Ryckaert, A. Funke, C. Vervaet, D. Djuric, J. Dhondt, I. Nopens   +17 more
core   +1 more source

Development of a process map : a step towards a regime map for steady-state high shear wet twin screw granulation

, 2016
Twin-screw granulation is an emerging continuous granulation technique in the pharmaceutical industry. The flexibility in process settings such as the binder addition method (wet vs.
Remon, Jean Paul, De Beer, Thomas, Vervaet, Chris, Gernaey, Krist V., Nopens, Ingmar, De Leersnyder, Fien, Vanhoorne, Valérie, Vercruysse, Jurgen, Dhondt, Jens, Kumar, Ashish, Gernaey, Krist   +10 more
core   +1 more source

Interplay Between Semi-Continuous Blending and Continuous Twin-Screw Wet Granulation: Impact of Blend Uniformity on CQAs of Low-Dose Granules

Achieving a uniform powder mixture in low-dose and complex formulations is inherently challenging and can undermine downstream process performance and product quality.
Tsolmon Erelkhegbataar, Fabian Starsich, Louis Bouckaert, Chris Vervaet, Valérie Vanhoorne, Daan Janssens   +5 more
core   +1 more source

Twin screw granulation: A detailed study

, 2012
Granulation is the process by which a large number of fine particles (primary particles) are agglomerated together in the presence of a liquid to form a smaller number of larger particles (granules).
Dhenge, Ranjitkumar
core  

Granule breakage in twin screw granulation: Effect of material properties and screw element geometry

, 2017
© 2017 Elsevier B.V.This study is the first to explicitly measure the influence of material dynamic yield strength (DYS) and screw element geometry on the breakage process in twin screw granulation.
Sen, M., Maitraye Sen, Jiayu Li, Pradhan, S.U., Li, J., Wassgren, C.R., Litster, J.D., Carl R. Wassgren, Shankali U. Pradhan, James D. Litster   +9 more
core   +1 more source

Twin Screw Melt Granulation: A Single Step Approach for Developing Self-Emulsifying Drug Delivery System for Lipophilic Drugs. [PDF]

Pharmaceutics, 2023
Nyavanandi D, Mandati P, Narala S, Alzahrani A, Kolimi P, Vemula SK, Repka MA.   +6 more
europepmc   +1 more source

Using a Material Library to Understand the Change of Tabletability by High Shear Wet Granulation. [PDF]

Pharmaceutics, 2022
Wang Y, Cao J, Zhao X, Liang Z, Qiao Y, Luo G, Xu B.   +6 more
europepmc   +1 more source

Continuous twin screw wet granulation of low-dose formulations : impact of process variables and API/binder addition methods on granule quality attributes

Continuous manufacturing technologies such as twin-screw wet granulation (TSWG) offer advantages over batch processing but face challenges when producing low-dose formulations.
Portier, Christoph, Vervaet, Chris, Vanhoorne, Valérie, Bouckaert, Louis, Adamo, Giorgia, Ombecq, Mathieu   +5 more
core   +1 more source

Continuous twin screw granulation - An advanced alternative granulation technology for use in the pharmaceutical industry. [PDF]

Int J Pharm, 2020
Bandari S, Nyavanandi D, Kallakunta VR, Janga KY, Sarabu S, Butreddy A, Repka MA.   +6 more
europepmc   +1 more source