Evaluation of Process Parameters for Continuous Manufacturing of Quetiapine Fumarate Immediate Release Tablets Using Twin Screw Wet Granulation. [PDF]
Pharm ResGranulation is one of the important unit operations in the manufacturing of solid dosage forms like tablets and capsules that regulate the quality of end products.
Naguboyina T +4 more
europepmc +2 more sources
Twin-Screw Melt Granulation for Oral Solid Pharmaceutical Products. [PDF]
Pharmaceutics, 2021 This article highlights the advantages of pharmaceutical continuous melt granulation by twin-screw extrusion. The different melt granulation process options and excipients are described and compared, and a case is made for expanded use of twin-screw melt
Forster SP, Dippold E, Chiang T.
europepmc +2 more sources
Twin Screw Wet Granulation With Various Hydroxypropyl Methylcellulose (HPMC) Grades [PDF]
, 2022 Twin screw wet granulation has been proved as a feasible alternative for traditional batch granulation process due to its continuous processing feature; considered as a significant processing method especially in the pharmaceutical industry.
Chen, Jingyi
core +2 more sources
Advances in twin-screw granulation
, 2021 Twin-screw granulation (TSG) is an emerging process technology that allows both wet and dry granulation of powders with a wide range of properties [...
Vanhoorne, Valérie +3 more
core +1 more source
Parametric Study of Residence Time Distributions and Granulation Kinetics as a Basis for Process Modeling of Twin-Screw Wet Granulation [PDF]
, 2021 Twin-screw wet granulation is a crucial unit operation in shifting from pharmaceutical batch to continuous processes, but granulation kinetics as well as residence times are yet poorly understood.
Sivanesapillai, Rakulan +7 more
core +1 more source
, 2023 Population balance models (PBM) have been widely used to model the twin-screw wet granulation (TSWG) in the continuous manufacturing of solid dosage forms.
Matsunami, KensakuFW020001907414068020037291790000-0002-8831-018Xfa74b9bb-f129-11e9-843f-92d8df47a88d +8 more
core +2 more sources
SCALE-UP OF PHARMACEUTICAL TWIN-SCREW WET GRANULATION BASED ON THE PROCESS SIMULATION USING GENETIC PROGRAMMING [PDF]
, 2023 Wet granulation is a crucial process in the manufacturing of pharmaceutical tablets. For several years, twin-screw wet granulation has been noticeably studied as a continuous method for granulation in the pharmaceutical industry because of its ability ...
Mozumder, Sumon
core +2 more sources
Continuous twin-screw melt granulation of poorly compressible and thermal labile drug [PDF]
, 2021 Continuous twin-screw melt granulation (TSMG) has been widely used for the last 50 years in various industrial processes. For pharmaceutical manufacturing, TSMG offers many advantages over continuous twin-screw wet granulation and roller compaction ...
Kittikunakorn, Nada
core +1 more source
TWIN SCREW WET AND DRY GRANULATION [PDF]
, 2017 Twin screw granulation has gained wide interest by pharmaceutical manufacturing and the industry is still trying to expand its application. This thesis will further explore this technique and try to develop a new granulation strategy based on similar ...
Liu, Yang
core +1 more source
Understanding Scalability In A Twin Screw Wet Granulation [PDF]
, 2022 Continuous wet granulation using a twin-screw extruder has attracted considerable attentions in pharmaceutical industry as it ensures consistent tablet quality at a high production rate.
Shi, Zequn
core +2 more sources