Results 141 to 150 of about 2,453,712 (230)

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Alamandine/MrgD pathway modulates gut–bone marrow axis in ageing

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ageing is associated with colon epithelial barrier disruption and up‐regulation of myelopoiesis in the bone marrow (BM). Alamandine (Ala) and MrgD are novel members of the renin angiotensin system (RAS). This study tested the hypothesis that Ala restores the colon epithelial barrier integrity in ageing via modulating gut–
Kishore Chittimalli   +6 more
wiley   +1 more source

Microwave ablation for twin-reversed arterial perfusion sequence. [PDF]

open access: yesBMJ Case Rep
Kongwattanakul K   +3 more
europepmc   +1 more source

Oral Butyrate Reduces Progression of Kidney Damage in an L‐NAME‐Induced Diabetic Kidney Disease Mouse Model

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Diabetic kidney disease (DKD) is one of the main causes of kidney failure worldwide. Interestingly, patients affected by DKD are characterised by a low abundance of gut bacteria producing short fatty acids including butyrate, which is suggested to play a role in the decline of renal function.
Maria Novella Nicese   +13 more
wiley   +1 more source

Trap (twin reversed arterial perfusion ) sequence

open access: yes, 2009
TRAP sekansı monokoryonik ikiz gebeliklerde 1/100 oranında görülen kötü prognoza sahip bir fenomendir. TRAP sekansında multipl anomalilere sahip, kalbi gelişmemiş “nonviable” bir fetus ile bu fetusu plasentadaki vasküler anastomozlar yoluyla besleyen ...
Kazandı, M.   +4 more
core  

Cisterna Chyli Dilation Is a Risk Factor for Liver Nodules and Hepatocellular Carcinoma in Fontan‐Associated Liver Disease: Pathophysiological Role of Lymphatic Dysfunction

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto   +14 more
wiley   +1 more source

Assessment of Learning Curve for Radiofrequency Ablation in Twin Reversed Arterial Perfusion Sequence: A Simulation Model Study. [PDF]

open access: yesPrenat Diagn
Chaiperm T   +6 more
europepmc   +1 more source

Multiscale analysis of the adult human superior hypogastric plexus and hypogastric nerve

open access: yesJournal of Anatomy, EarlyView.
Using tissue clearing and light‐sheet microscopy methods, we visualized the 3D mesoscopic arrangement of neural tracts, blood vessels and neurons within the adult human superior hypogastric plexus and hypogastric nerves, identifying the latter to contain thousands of neuronal cells bodies embedded along its entire length.
Kayleigh S. Scotcher   +4 more
wiley   +1 more source

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