Results 81 to 90 of about 361,014 (259)
A placebo-controlled trial of folic acid and betaine in identical twins with Angelman syndrome. [PDF]
, 2019 BackgroundAngelman syndrome (AS) is a neurodevelopmental disorder that is caused by maternal genetic deficiency of a gene that encodes E6-AP ubiquitin-protein ligase (gene symbol UBE3A) mapping to chromosome 15q11-q13.
Anselm, Irina +8 more
core
Genetic Susceptibility to Periodontitis
Journal of Periodontal Research, EarlyView.Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source
Whole genome and exome sequencing of monozygotic twins with trisomy 21, discordant for a congenital heart defect and epilepsy. [PDF]
PLoS ONE, 2014 Congenital heart defects (CHD) occur in 40% of patients with trisomy 21, while the other 60% have a structurally normal heart. This suggests that the increased dosage of genes on chromosome 21 is a risk factor for abnormal heart development.
Pongsathorn Chaiyasap +5 more
doaj +1 more source
Die Sprachentwicklung von Ein-und Zweieiigen Zwillingen und die Vererbung von Sprachstörungen [PDF]
, 2017 The genetic roots of speech development in children are being investigated. On the basis of observations in the development of speech in 12 monozygotic twin pairs it could be shown that not only the retarded but also the normal development of speech is ...
Luchsinger, R.
core
Stem-Like Adaptive Aneuploidy and Cancer Quasispecies [PDF]
, 2013 We analyze and reinterpret experimental evidence from the literature to argue for an ability of tumor cells to self-regulate their aneuploidy rate. We conjecture that this ability is mediated by a diversification factor that exploits molecular mechanisms
Napoletani, Domenico +2 more
core +4 more sources
Epigenetics, 2012 We describe monozygotic twins discordant for childhood leukemia and secondary thyroid carcinoma. We used bisulfite pyrosequencing to compare the constitutive promoter methylation of BRCA1 and several other tumor suppressor genes in primary fibroblasts ...
D. Galetzka +12 more
semanticscholar +1 more source
Sleep and Maladaptive Personality Traits: A Twin Study
Journal of Sleep Research, EarlyView.ABSTRACT Sleep is essential for human functioning, but little attention has been paid to the interplay between sleep and maladaptive personality traits. We examined genetic and environmental associations between sleep and four maladaptive domains (MDs)—Negative Affectivity, Detachment, Disinhibition, and Psychoticism—within the framework of the DSM‐5 ...
Ziyu Ren +11 more
wiley +1 more source
European PsychiatryBackground Depression affects twice as many women as men. Risk factors for depression certainly impact this difference, but their strong interconnectedness challenges the assessment of standalone contributions.
Daiyan Zhang, Maria Semkovska
doaj +1 more source
Public Health Professionals’ Perceptions on Intertwin Relationship in Multiple‐Birth Family Nursing
Public Health Nursing, EarlyView.ABSTRACT Objective To describe how dominance, submissiveness, and speaking role appear in the intertwin relationship between twins under 7 years old. Design and Sample A cross‐sectional study design was used. The respondents (n = 72) were nurses. Information about the intertwin relationship was explored through Likert‐scale statements and open‐ended ...
Kristiina Heinonen +3 more
wiley +1 more source
Marital Status and Unobserved Heterogeneity - Do twins suggest a genetic inheritance? [PDF]
The purpose of this study is to reveal the importance of unobserved heterogeneity on marital status. The results for monozygotic (identical) and dizygotic twins indicate an important genetic component in marital status.
Nilsson, William
core +1 more source