Results 71 to 80 of about 233,077 (337)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

B →P and B →V form factors from B-meson light-cone sum rules beyond leading twist

Journal of High Energy Physics, 2019
We provide results for the full set of form factors describing semileptonic B-meson transitions to pseudoscalar mesons π, K, D ¯ $$ \overline{D} $$ and vector mesons ρ, K ∗, D ¯ ∗ $$ {\overline{D}}^{\ast } $$ .
N. Gubernari, A. Kokulu, D. van Dyk
doaj   +1 more source

Quality-adjusted Time Without Symptoms of disease or Toxicity (Q-TWiST) analysis of CPX-351 versus 7 + 3 in older adults with newly diagnosed high-risk/secondary AML

Journal of Hematology & Oncology, 2021
Background CPX-351 (United States: Vyxeos®; Europe: Vyxeos® Liposomal), a dual-drug liposomal encapsulation of daunorubicin and cytarabine in a synergistic 1:5 molar ratio, is approved by the US FDA and the EMA for the treatment of adults with newly ...
Jorge E. Cortes, Tara L. Lin, Geoffrey L. Uy, Robert J. Ryan, Stefan Faderl, Jeffrey E. Lancet   +5 more
doaj   +1 more source

Elastic continuum theory: Fully understanding of the twist-bend nematic phases

, 2015
The twist-bend nematic phase, $N_{\rm TB}$, may be viewed as a heliconical molecular arrangement in which the director $\bf n$ precesses uniformly about an extra director field, $\bf t$.
Barbero, Giovanni, Evangelista, Luiz Roberto, Lelidis, Ioannis, Rosseto, Michely Patrícia, Zola, Rafael Soares   +4 more
core   +1 more source

Long-wavelength torsional modes of solar coronal plasma structures [PDF]

, 2010
Aims. We consider the effects of the magnetic twist and plasma rotation on the propagation of torsional m = 0 perturbations of cylindrical plasma structures (straight magnetic flux tubes) in the case when the wavelength is much longer than the cylinder ...
Nakariakov, V. M. (Valery M.), Van Doorsselaere, Tom, Vasheghani Farahani, Soheil   +2 more
core   +1 more source

Nanoparticle-induced twist-grain boundary phase

Physical Review E, 2014
By means of high-resolution ac calorimetry and polarizing optical microscopy, it is demonstrated that surface-functionalized spherical CdSSe nanoparticles induce a twist-grain boundary phase when dispersed in a chiral liquid crystal. These nanoparticles can effectively stabilize the one-dimensional lattice of screw dislocations, thus establishing the ...
Trček, M., Cordoyiannis, G., Tzitzios, V., Kralj, S., Nounesis, G., Lelidis, I., Kutnjak, Z.   +6 more
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Quality-adjusted Time Without Symptoms or Toxicity (Q-TWiST) for Lenvatinib plus Everolimus Versus Everolimus Monotherapy in Patients with Advanced Renal Cell Carcinoma

European Urology Open Science, 2021
Background: The lenvatinib (LEN) plus everolimus (EVE) combination demonstrated improved progression-free survival over everolimus alone in a phase 2 trial (Study-205).
Chung-Han Lee, Yin Wan, Alan Smith, Ran Xie, Robert J. Motzer   +4 more
doaj   +1 more source

Theory of Polar Blue Phases

, 2014
In liquid crystals, if flexoelectric couplings between polar order and director gradients are strong enough, the uniform nematic phase can become unstable to formation of a modulated polar phase.
Allender, David W., Selinger, Jonathan V., Shamid, Shaikh M.   +2 more
core   +1 more source

Comparative analysis of anisotropic material properties of uniaxial nematics formed by flexible dimers and rod-like monomers [PDF]

, 2016
We report temperature dependencies of material properties such as dielectric anisotropy, birefringence, splay (K₁₁), twist (K₂₂), and bend (K₃₃) elastic constants of the uniaxial nematic (N) phase formed by flexible dimers of DTC5C9 and compare their ...
Ahmed, Z., Cukrov, Greta, Lavrentovich, Oleg D., Mehl, G. H., Mosaddeghian Golestani, Youssef, Nastishin, Yu A., Welch, C., Xiang, Jie   +7 more
core   +2 more sources