Results 51 to 60 of about 39,618 (259)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Tunable Electronic Structure in Twisted Bilayer WTe2

open access: yesFrontiers in Physics, 2022
The moiré pattern restricts the electronic states of transition metal bilayers, thus extending the concept of the magic angle found in twisted bilayer graphene to semiconductors.
Zi-Si Chen   +11 more
doaj   +1 more source

Berry phase transition in twisted bilayer graphene

open access: yes2D Materials, 2016
20 pages main paper + 10 pages supporting ...
Rode, Johannes C.   +3 more
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

B →P and B →V form factors from B-meson light-cone sum rules beyond leading twist

open access: yesJournal of High Energy Physics, 2019
We provide results for the full set of form factors describing semileptonic B-meson transitions to pseudoscalar mesons π, K, D ¯ $$ \overline{D} $$ and vector mesons ρ, K ∗, D ¯ ∗ $$ {\overline{D}}^{\ast } $$ .
N. Gubernari, A. Kokulu, D. van Dyk
doaj   +1 more source

Dispersion Analysis of Periodically Loaded Transmission Lines with Twist Symmetry Using the Mode-Matching Technique

open access: yesApplied Sciences, 2020
A mode-matching formulation is presented and used to analyze the dispersion properties of twist-symmetric transmission lines. The structures are coaxial lines periodically loaded with infinitely thin screens, which are rotated with respect to each other ...
Oskar Zetterstrom   +5 more
doaj   +1 more source

Quality-adjusted Time Without Symptoms of disease or Toxicity (Q-TWiST) analysis of CPX-351 versus 7 + 3 in older adults with newly diagnosed high-risk/secondary AML

open access: yesJournal of Hematology & Oncology, 2021
Background CPX-351 (United States: Vyxeos®; Europe: Vyxeos® Liposomal), a dual-drug liposomal encapsulation of daunorubicin and cytarabine in a synergistic 1:5 molar ratio, is approved by the US FDA and the EMA for the treatment of adults with newly ...
Jorge E. Cortes   +5 more
doaj   +1 more source

Quality-adjusted Time Without Symptoms or Toxicity (Q-TWiST) for Lenvatinib plus Everolimus Versus Everolimus Monotherapy in Patients with Advanced Renal Cell Carcinoma

open access: yesEuropean Urology Open Science, 2021
Background: The lenvatinib (LEN) plus everolimus (EVE) combination demonstrated improved progression-free survival over everolimus alone in a phase 2 trial (Study-205).
Chung-Han Lee   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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