Results 51 to 60 of about 39,618 (259)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Tunable Electronic Structure in Twisted Bilayer WTe2
The moiré pattern restricts the electronic states of transition metal bilayers, thus extending the concept of the magic angle found in twisted bilayer graphene to semiconductors.
Zi-Si Chen +11 more
doaj +1 more source
Berry phase transition in twisted bilayer graphene
20 pages main paper + 10 pages supporting ...
Rode, Johannes C. +3 more
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
B →P and B →V form factors from B-meson light-cone sum rules beyond leading twist
We provide results for the full set of form factors describing semileptonic B-meson transitions to pseudoscalar mesons π, K, D ¯ $$ \overline{D} $$ and vector mesons ρ, K ∗, D ¯ ∗ $$ {\overline{D}}^{\ast } $$ .
N. Gubernari, A. Kokulu, D. van Dyk
doaj +1 more source
A mode-matching formulation is presented and used to analyze the dispersion properties of twist-symmetric transmission lines. The structures are coaxial lines periodically loaded with infinitely thin screens, which are rotated with respect to each other ...
Oskar Zetterstrom +5 more
doaj +1 more source
Background CPX-351 (United States: Vyxeos®; Europe: Vyxeos® Liposomal), a dual-drug liposomal encapsulation of daunorubicin and cytarabine in a synergistic 1:5 molar ratio, is approved by the US FDA and the EMA for the treatment of adults with newly ...
Jorge E. Cortes +5 more
doaj +1 more source
Background: The lenvatinib (LEN) plus everolimus (EVE) combination demonstrated improved progression-free survival over everolimus alone in a phase 2 trial (Study-205).
Chung-Han Lee +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

