Results 51 to 60 of about 2,169,353 (266)

High-throughput transposon sequencing identifies HprR as a key regulator of the LEE operon and virulence in E. coli O157:H7

open access: yesVirulence
Enterohemorrhagic Escherichia coli (EHEC) comprises a prominent group of extracellular human pathogens that specifically colonize the colonic epithelium, leading to severe gastrointestinal diseases and representing a significant global public health ...
Miaomiao Liu   +11 more
doaj   +1 more source

Genetic Variations in Staphylococcus aureus Two-Component Systems and Antimicrobial Stress Responses [PDF]

open access: yesBasrah Journal of Veterinary Research
Staphylococcus aureus utilizes two-component signal transduction systems (TCSs) for sensing and responding to stressors such as antimicrobials. Variations in the sequence of TCSs involved in antimicrobial resistance, such as WalRK, VraSR, LytSR, GraSR ...
Mohammed Al-Bukhalifa, Hassan Al-Tameemi
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

The NtrYX Two-Component System Regulates the Bacterial Cell Envelope

open access: yesmBio, 2020
Activity of the NtrYX two-component system has been associated with important processes in diverse bacteria, ranging from symbiosis to nitrogen and energy metabolism.
Kimberly C. Lemmer   +9 more
doaj   +1 more source

Prospects of creation of the two-component nuclear energy system [PDF]

open access: yesNuclear Energy and Technology, 2019
Possible options of organization of two-component energy system with closed nuclear fuel cycle (CNFC) and new business potential associated with provision of CFC services to foreign customers are examined.
Andrey Yu. Petrov   +5 more
doaj   +3 more sources

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge   +6 more
wiley   +1 more source

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita   +5 more
wiley   +1 more source

Two-Component Regulatory Systems of Mycobacteria

open access: yesMicrobiology Spectrum, 2014
ABSTRACT Two-component regulatory systems (2CRSs) are widely used by bacteria to sense and respond to environmental stimuli with coordinated changes in gene expression. Systems are normally comprised of a sensory kinase protein that activates a transcriptional regulator by phosphorylation.
openaire   +2 more sources

Disruption of Two-component System LytSR Affects Forespore Engulfment in Bacillus thuringiensis

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Two-component regulatory systems (TCSs) play pivotal roles in bacteria sensing many different stimuli from environment. Here, we investigated the role of the LytSR TCS in spore formation in Bacillus thuringiensis (Bt) subsp. kurstaki HD73.
Qi Peng   +7 more
doaj   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte   +5 more
wiley   +1 more source

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