Results 51 to 60 of about 38,435,768 (244)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
A hybrid genetic algorithm and tabu search approach for post enrolment course timetabling [PDF]
, 2010 Copyright @ Springer Science + Business Media. All rights reserved.The post enrolment course timetabling problem (PECTP) is one type of university course timetabling problems, in which a set of events has to be scheduled in time slots and located in ...
Yang, S +4 more
core +1 more source
FibersThe use of a carbon-fiber-reinforced polymer (CFRP) for structural strengthening has been widely adopted in recent decades. Early studies focused on externally bonded (EB) techniques, but premature delamination of CFRP from concrete surfaces often ...
Ahmed H. Al-Abdwais, Adil K. Al-Tamimi
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Energies, 2021 Decision-making is a crucial and difficult step in the design process of complex systems such as the hybrid powertrain. Finding an optimal solution requires the system feedback.
Adham Kaloun +4 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
NG-MVEE: A New Proposed Hybrid Technique for Enhanced Mitigation of Code Re-Use Attack
IEEE Access, 2023 Code-Reuse Attacks (CRAs) are solid mechanisms to bypass advanced software and hardware defenses because they use the software’s own code and they are very hard to be detected without significant overhead.
Ayman M. El-Zoghby +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Repair Techniques for Hybrid Nano/CMOS Computational Architecture
, 2009 —Presence of high defect rate in nanofabrics due to the inadequate fabrication processes has held back the development of emerging technology architecture. In this work, we propose two repair techniques to provide high level of defect tolerance in lookup
Srivastava, Saket +2 more
core +1 more source
Investigating Global Stability and Bifurcation in an Ecological Dynamical System
ComplexityWe consider a continuous-time model describing the interaction between phytoplankton and zooplankton using a Holling type-II response. We then transform this continuous-time model into a discrete-time counterpart using a fractional-order discretization ...
Muhammad Salman Khan +3 more
doaj +1 more source