Results 61 to 70 of about 38,435,768 (244)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Word shape analysis for a hybrid recognition system [PDF]

, 1997
This paper describes two wholistic recognizers developed for use in a hybrid recognition system. The recognizers use information about the word shape. This information is strongly related to word zoning.
Whitrow, RJ, Powalka, RK, Sherkat, N
core  

Hybrid solar geothermal setup by optimal retrofitting

Case Studies in Thermal Engineering, 2021
Majority of power generation plants in India depends on non-renewable resource as a fuel due to low cost and ready availability. Usage of non-renewable resources for power generation on the other hand is expensive and less reliable.
Namrata Bist, Anirbid Sircar
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Qualified Two-Hybrid Techniques by DWT Output to Predict Fault Location [PDF]

, 2020
The power transmission system is essential for the power scheme to transfer the energy from generators to consumers. The short circuit problem repeatedly occurs in the transmission system, and the main problem is to separate the sources from users.
Ahmad, Sandy; Universitas Riau, Azhari Zakri, Azriyenni; Universitas Riau, Mustafa, Mohd Wazir; Universiti Teknologi Malaysia, Darmawan, Syukri; Universitas Riau, Usman, Jafaru; University of Maiduguri Borno State, Jafaru Usman, Azriyenni Azhari Zakri, Sandy Ahmad, Mohd Wazir Mustafa, Syukri Darmawan   +9 more
core   +5 more sources

On suboptimal control design for hybrid automata using predictive control techniques [PDF]

, 2005
In this paper we propose an on-line design technique for the target control problem, when the system is modelled by hybrid automata. First, we compute off-line the shortest path, which has the minimum discrete cost, from an initial state to the given ...
Pang, Yan, Spathopoulos, Michael P., Raisch, Joerg   +2 more
core   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Building Switching Hybrid Recommender System Using Machine Learning Classifiers and Collaborative Filtering

, 2010
Recommender systems apply machine learning and data mining techniques for filtering unseen information and can predict whether a user would like a given resource.
Prugel-Bennett, Adam, Ghazanfar, Mustansar   +1 more
core   +1 more source

Analytical solutions of some time-fractional versions of the coupled KdV system of equations via two hybrid transform techniques

Scientific Reports
In this work, two efficient hybrid transform methods known as the natural homotopy perturbation method (NHPM) and the $$q-$$ homotopy analysis transform method ( $$q-$$ HATM) are utilised to investigate analytical solutions of the time-fractional coupled
K. Aruna, N. I. Okposo, P. Veeresha, K. Raghavendar   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source