Results 31 to 40 of about 18,592,418 (173)

Speed Reduction Capabilities of Two-Geometry Roundabouts

open access: yesApplied Sciences, 2023
Several types of modern roundabouts are alternatives to standard ones. They are either in use or at the development stage today. One such intersection is the two-geometry roundabout.
Saša Ahac   +3 more
doaj   +1 more source

Mechanical Caging of Nucleic Acids Enabled by Light‐Activated Synthetic Molecular Motors

open access: yesAngewandte Chemie, EarlyView.
A synthetic light‐driven molecular motor imposes mechanical constraints on nucleic acids, enabling “mechanical caging” as a new mode to regulate DNA structure and function through mechanical input rather than chemical masking. ABSTRACT Control over nucleic acid activity is central to biotechnology and therapeutic development.
Yuchen Ma   +10 more
wiley   +2 more sources

The Surrogate Safety Appraisal of the Unconventional Elliptical and Turbo Roundabouts

open access: yesJournal of Advanced Transportation, 2018
Double-lane roundabouts have been created in many European countries over the past few centuries and are now characterized by an unsafe geometric development and by a low sustainability capacity or level.
Giovanni Tesoriere   +3 more
doaj   +1 more source

Effects of Crosswalk Location and Pedestrian Volume on Entry Capacity of Roundabouts

open access: yesInternational Journal of Transportation Science and Technology, 2013
At roundabout approaches, vehicles must yield to pedestrians who are using crosswalks. The presence of pedestrians using the crosswalk at a roundabout approach thus decreases the entry capacity of the approach. This research used a calibrated microscopic
Carlos Duran, Ruey Cheu
doaj   +1 more source

Capacity Model for Single-Lane Minor Entry at Turbo-Roundabouts

open access: yesCivil and Environmental Engineering, 2021
Spirally arranged and physically separated traffic lanes in the circulatory carriageway of turbo-roundabouts force drivers to choose a particular entry lane and, subsequently, a circulatory traffic lane according to their intended destination.
Kociánová Andrea
doaj   +1 more source

Characteristics of Drivers\u27 Lane Choice at Large Multi-lane Roundabout [PDF]

open access: yes, 2020
The use of modern roundabout as an intersection treatment is a popular choice. To increase the capacity, large multi-lane roundabout has been implemented to solve traffic congestions.
Saif Al-Mamari, Rahma Naser   +1 more
core  

Iterative Selection of DNA Nanostructures for Cellular Uptake

open access: yesAdvanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar   +4 more
wiley   +1 more source

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

open access: yesAdvanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan   +10 more
wiley   +1 more source

Effect of Signing and Lane Markings on the Safety of a Two-Lane Roundabout [PDF]

open access: yes, 2014
This report presents a study of the impact lane markings and signing have on driving behavior at a two-lane roundabout located in Richfield, Minnesota. After its completion in 2008, this roundabout sustained a suspiciously high amount of crashes.
Hourdos, John   +2 more
core  

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

open access: yesAdvanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li   +8 more
wiley   +1 more source

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