Results 41 to 50 of about 809 (160)

Capacity Model for Single-Lane Minor Entry at Turbo-Roundabouts

open access: yesCivil and Environmental Engineering, 2021
Spirally arranged and physically separated traffic lanes in the circulatory carriageway of turbo-roundabouts force drivers to choose a particular entry lane and, subsequently, a circulatory traffic lane according to their intended destination.
Kociánová Andrea
doaj   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan   +12 more
wiley   +1 more source

ROAD TRAFFIC SAFETY-RELATED CHANGES INTRODUCED ON T. KOŚCIUSZKI AND KRÓLOWEJ JADWIGI STREETS IN DĄBROWA GÓRNICZA BETWEEN 2006 AND 2015 [PDF]

open access: yesScientific Journal of Silesian University of Technology. Series Transport, 2017
This article discusses the results of an analysis of road traffic safety-related changes introduced in T. Kościuszki and Królowej Jadwigi Streets in Dąbrowa Górnicza between 2006 and 2015.
Elżbieta MACIOSZEK   +1 more
doaj   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

Bandgap‐Engineered PtxTey:Ag2Te Composite Quantum Dots Enable Programmable NIR‐II Imaging and Photothermal‐Immune Synergistic Therapy

open access: yesAdvanced Science, EarlyView.
A bandgap‐engineered PtxTey:Ag2Te quantum dot platform enables tunable NIR‐IIb emission for deep‐tissue imaging and mild photothermal therapy. Conjugation with αPD‐L1 confers dual tumor targeting and real‐time monitoring of PD‐L1 dynamics. Mild photothermal modulation induces immune reprogramming, enhancing checkpoint blockade efficacy and achieving ...
Jing Liu   +9 more
wiley   +1 more source

Cycling at intersections: a multi-objective assessment for traffic, emissions and safety

open access: yesTransport, 2019
This paper evaluated in an integrated manner the traffic performance, pollutant emissions and road conflicts between bicycles and motor vehicles at a signalized intersection.
Behnam Bahmankhah   +2 more
doaj   +1 more source

Functional anatomy, jaw mechanisms, and feeding behavior of Dunkleosteus terrelli (Placodermi, Arthrodira)

open access: yesThe Anatomical Record, EarlyView.
A new musculoskeletal reconstruction and revision of the cranio‐mandibular anatomy of the Devonian arthrodire placoderm Dunkleosteus terrelli from a comparative and functional anatomical perspective. Dunkleosteus is a specialized arthrodire with many specializations for feeding on large vertebrates, and many of its features are part of broader ...
Russell K. Engelman   +4 more
wiley   +1 more source

Selection of Intersection Control Type in Urban Areas

open access: yesCivil and Environmental Engineering, 2022
In Egypt, urban planning projects usually do not consider the intersection type. This study developed charts for practitioners that could be used to determine the optimal intersection.
Ramadan Ibrahim M. I.   +2 more
doaj   +1 more source

A Modular Nucleoside Kinase Cascade for the Synthesis of Ribonucleoside Triphosphates

open access: yesBiotechnology and Bioengineering, EarlyView.
Damm et al. report standardized enzymatic cascades for production of all canonical nucleoside triphosphates from the corresponding nucleosides, using kinase‐catalyzed phosphorylation from acetyl phosphate. Reactions afforded ∼ 100 mM product in near‐quantitative conversion.
Oliver T. Damm   +3 more
wiley   +1 more source

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