Results 61 to 70 of about 19,604,431 (252)

Two classes of visual motion sensitive interneurons differ in direction and velocity dependency of in vivo calcium dynamics [PDF]

, 2001
Dürr V, Kurtz R, Egelhaaf M. Two classes of visual motion sensitive interneurons differ in direction and velocity dependency of in vivo calcium dynamics. Journal of neurobiology. 2001;46(4):289-300.Neurons exploit both membrane biophysics and biochemical
Egelhaaf, Martin ; https://orcid.org/, Kurtz, Rafael, Dürr, Volker ; https://orcid.org/   +2 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Design and Modelling of a Two-Axis Compliant Joint Based on Flexure Leaf Springs

Machines
In the field of parallel robots, traditional rigid joints compromise motion accuracy owing to inherent friction and backlash, thus driving the demand for high-performance compliant joints.
Kuncheng Feng, Hasiaoqier Han, Changzheng Chen, Jiaxin Li, Haifei Hu, Kai Zhang, Zhenbang Xu   +6 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Pattern-Dependent Response Modulations in Motion-Sensitive Visual Interneurons-A Model Study [PDF]

, 2011
Meyer HG, Lindemann JP, Egelhaaf M. Pattern-Dependent Response Modulations in Motion-Sensitive Visual Interneurons-A Model Study. PLoS ONE. 2011;6(7): e21488.Even if a stimulus pattern moves at a constant velocity across the receptive field of motion ...
Lindemann, Jens Peter ; https://orcid.org/, Hanno Gerd Meyer, Egelhaaf, Martin ; https://orcid.org/, Jens Peter Lindemann, Martin Egelhaaf, Meyer Hanno Gerd, Meyer, Hanno Gerd, Lindemann Jens Peter, Egelhaaf Martin   +8 more
core   +2 more sources

FlectoSol – A pneumatically activable PV-functionalized façade shading module with bending motion in two directions for solar tracking

Developments in the Built Environment
A continuously adjustable façade shading system functionalized with photovoltaics enables, besides adaptive shading, energy harvesting by solar tracking. This requires large bending motion in two directions.
Larissa Born, Edith Anahi González San Martín, Matthias Ridder, Axel Hannes Körner, Jan Knippers, Götz T. Gresser   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Parametric and Multiobjective Optimization with Applications in Finance [PDF]

, 2010
In this thesis parametric analysis for conic quadratic optimization problems is studied. In parametric analysis, which is often referred to as parametric optimization or parametric programming, a perturbation parameter is introduced into the ...
Romanko, Oleksandr
core  

Classifiers Combination for Improved Motion Segmentation

, 2004
. Multiple classifiers have shown capability to improve performance in pattern recognition. This process can improve the overall accuracy of the system by using an optimal decision criteria.
Gunn, S. R., Al-Mazeed, A. H., Nixon, M. S.   +2 more
core   +2 more sources