Results 71 to 80 of about 19,604,431 (252)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Analysis of the coupling effect of water on deck and parametric rolling motion in regular waves

open access: yesZhongguo Jianchuan Yanjiu
ObjectivesParametric rolling and green water on deck are two critical nonlinear phenomena closely related to ship motion stability, particularly under severe sea conditions.
Jiarun ZHANG   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Drgania Parametryczne Jednostopniowej Przekładni Zębatej

open access: yesEngineering Transactions, 1972
The subject of the investigations is the theoretical analysis of parametric vibrations of a simple gear transmission produced by periodic variations of the toothing rigidity.
R. Gryboś
doaj  

Repeatability of scapular motion tracking in individuals with high body mass index

open access: yesFrontiers in Sports and Active Living
IntroductionScapular motion tracking is essential for understanding shoulder kinematics, but its utility in individuals with high body mass index (BMI) requires further investigation.
Angelica E. Lang   +2 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Weigh-in-Motion: Recent Developments in Europe [PDF]

open access: yes, 2012
4th International Conference on Weigh-in-Motion - ICWIM4, Taipei, Taiwan, 20-23rd February 2005This paper provides a review of recent European developments in WIM.
Jacob, Bernard, O'Brien, Eugene J.
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

4th Annual Two-Spirit Pow Wow, San Francisco

open access: yes, 2015
Color photograph from the 4th annual Two-Spirit Pow wow, far left in blue shirt Jay Armajo, holding United States Flag David Romero, eagle feather headdress and buckskin regalia Clide Hall, holding staff Liz Gamboa, possibly Lain in dark blue regalia ...
Bay Area American Indian Two Spirits
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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