Results 151 to 160 of about 17,766,923 (318)
Wet on wet landscape of green and red trees, brown and gray foreground and blue sky.Tiff file: 2020x3270 pixels, 18.9 Mb; Display: jpeg, 480x800 pixels ...
Father Edward Catich
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Wet on wet landscape of brown evergreen trees; brown, green and tan foreground; blue sky.Tiff file: 2000x3050 pixels, 17.5 Mb; Display: jpeg, 500x763 pixels ...
Father Edward Catich
core
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Landscape of red house with white roof and yellow house with green roof above. Incomplete figures on green foreground, trees in background, blue sky.Tiff file: 1960x3340 pixels, 18.7 Mb; Display: jpeg, 455x800 pixels ...
Father Edward Catich
core
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Wet on wet landscape with white, tan and red buildings, green trees in foreground, blue and red sky.Tiff file: 2440x3280 pixels, 22.9 Mb; Display: jpeg, 595x800 pixels ...
Father Edward Catich
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Wet on wet landscape of field in green, pink and yellow, brown trees in background and blue sky.Tiff file: 1680x2260 pixels, 10.9 Mb; Display: jpeg, 376x542 pixels ...
Catich, Father Edward Catich
core
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source

