Results 91 to 100 of about 22,687,746 (256)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Composite likelihood and two-stage estimation in family studies
, 2002 Composite likelihood; Two-stage estimation; Family studies; Copula; Optimal weights; All possible ...
Andersen, Elisabeth Anne Wreford
core +1 more source
Testing Categorized Bivariate Normality With Two-Stage Polychoric Correlation Estimates [PDF]
(WP 10/03 Clave pdf) We show that when the thresholds and the polychoric correlation are estimated in two stages, neither Pearson´s X² nor the likelihood ratio G² goodness of fit test statistics are asymptotically chi-square.We propose a new test ...
ALBERTO MAYDEU
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
MEASURING THE PERFORMANCE OF TWO-STAGE PRODUCTION SYSTEMS WITH SHARED INPUTS BY DATA ENVELOPMENT ANALYSIS [PDF]
As a non-parametric technique in Operations Research and Economics, Data Envelopment Analysis (DEA) evaluates the relative efficiency of peer production systems or decision making units (DMUs) that have multiple inputs and outputs.
A.B. Jaafar +3 more
core
Asymptotic optimality of a two-stage procedure in Bayes sequential estimation
, 2016 Asymptotically Bayes, Bayes sequential estimation, Empirical Bayes, Optimal sequential procedure, Two-stage procedure,
Jeng-Fu Liu +2 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Sleep Stage Estimation Comparing Own Past Heartrate or Others' Heartrate
SICE Journal of Control, Measurement, and System Integration, 2018 To increase the accuracy of real-time sleep stage estimation when only a small number of sleep data can be obtained such as after going to bed, the information for the subject's own sleep and other's past sleep can be used.
Yusuke Tajima +4 more
doaj +1 more source
Two-stage point estimation with a shrinkage stopping rule
Two-stage procedure, shrinkage estimation, domination of sample size, local alternatives, asymptotic risk,
T. Kubokawa, A. Saleh
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source