Results 81 to 90 of about 22,687,746 (256)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Bounded Risk Estimation of the Gamma Scale Parameter in a Purely Sequential Sampling Procedure
Journal of Statistical Theory and Applications (JSTA)We consider the purely sequential procedure for estimating the scale parameter of a gamma distribution with known shape parameter, when the risk function is bounded by the known preassigned number.
Eisa Mahmoudi +2 more
doaj +1 more source
Energies, 2015 A two-stage algorithm is proposed for the estimation of the fundamental frequency of asynchronously sampled signals in power systems. In the first stage, time-domain interpolation reconstructs the power system signal at a new sampling time and the ...
Joon-Hyuck Moon +4 more
doaj +1 more source
TWO-STAGE HUBER ESTIMATION [PDF]
In this paper we study how the Huber estimator can be adapted to the presence of endogeneity in a two stage equations setting similar to that of 2SLS. We propose an estimation procedure that is at the same time relatively (i) simple, (ii) robust and (iii)
Tae-Hwan Kim, Christophe Muller
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Russian Journal of Earth SciencesThe authors have developed a technology for estimating the parameters of non-stationary geophysical signals, using a two-stage approximation with local approximation models at the first stage and weighted averaging at the second stage.
Getmanov Viktor +3 more
doaj +1 more source
A Two-Stage Framework for Distortion Information Estimation and Underwater Image Restoration
PhotonicsThis work introduces a two-stage framework, named the Distorted underwater image Restoration Network (DR-Net), to address the complex degradation of underwater images caused by turbulence, water flow fluctuations, and optical properties of water.
Jianming Liu +7 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Robustness test of the Heckman two-stage estimation method.
Robustness test of the Heckman two-stage estimation method.
Caihong Wen (17904307)
core +1 more source