Results 121 to 130 of about 683,782 (308)

Robust estimation in simultaneous equations models [PDF]

, 1994
In this paper we review existing work on robust estimation for simultaneous equations models. Then we discuss three strategies for obtaining estimators with a high breakdown point, a controllable efficiency, and a reasonable computational cost: (a ...
Yohai, Víctor J., Maronna, Ricardo A.
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

A two-stage estimation approach for a radar system

, 2012
[[abstract]]In a, radar surveillance system, both non-maneuvering and, maneuveringconditions are usually existed, during the tracking process. The computation ofa, radar system, is more complicated, to track multiple maneuvering targets inreal situations.
Liu, W.-C. ; Chung, Yi-Nung; Lai, C.-W. ; Pan, T.-S. ; Hsu, C.-H.
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Improving multi-talker binaural DOA estimation by combining periodicity and spatial features in convolutional neural networks

EURASIP Journal on Audio, Speech, and Music Processing
Deep neural network-based direction of arrival (DOA) estimation systems often rely on spatial features as input to learn a mapping for estimating the DOA of multiple talkers.
Reza Varzandeh, Simon Doclo, Volker Hohmann   +2 more
doaj   +1 more source

An application of the two-stage, semi-parametric approach with double bootstrap to analyze technical efficiency of Critical Access Hospitals

This study examines technical efficiency of Critical Access Hospitals (CAH) using a two-stage approach and bootstrap procedures for making valid inference about the impact of environmental variables on CAH efficiency.
Nedelea, I. Cristian, Fannin, James Matthew   +1 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

A simple two-stage carrier-phase estimation algorithm for 32-QAM coherent optical communication systems

Frontiers in Physics
The combination of high-order modulation formats and linewidth-tolerant carrier phase estimation (CPE) can effectively improve spectrum efficiency and relax the limitation of laser linewidth.
Min Peng, Xiangqing Wang, Xiangqing Wang, Xiangqing Wang, Xiangqing Wang, Xiangqing Wang, Xiaokun Yang, Xiaokun Yang, Dongfei Wang, Dongfei Wang   +9 more
doaj   +1 more source

Power of significance test of dummies in Simar-Wilson two-stage efficiency analysis model

In this note we investigate the power of significance test for dummy-variables in the context of Simar and Wilson (2003) two-stage efficiency analysis model.truncated regression, production efficiency, dummy ...
Zelenyuk, Valentin
core