Results 131 to 140 of about 683,782 (308)

Estimation of state of charge of lithium-ion batteries usedin HEV using robust extended kalman filtering

, 2012
A robust extended Kalman filter (EKF) is proposed as a method for estimation of the state of charge (SOC) of lithium-ion batteries used in hybrid electric vehicles (HEVs). An equivalent circuit model of the battery, including its electromotive force (EMF)
jiang, J., Sharkh, S.M., Jiuchun Jiang, Caiping Zhang, Suleiman M. Sharkh, Weige Zhang, Zhang, C.P., Zhang, W.   +7 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

A two-stage randomized response technique for simultaneous estimation of sensitivity and truthfulness

Scientific Reports
Privacy protection is a critical concern when dealing with sensitive survey questions. Conventional randomized response (RR) models frequently fall short in providing respondents with adequate secrecy when assessing important parameters like the ...
Shehzad Ahmad Khan, Mohammed Ahmed Alomair, Moiz Qureshi, Abdullah Mohammed Alomair   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Two‐stage or not two‐stage? That is the question for IPD meta‐analysis projects

Individual participant data meta‐analysis (IPDMA) projects obtain, check, harmonise and synthesise raw data from multiple studies. When undertaking the meta‐analysis, researchers must decide between a two‐stage or a one‐stage approach.
Ensor, Joie, Morris, Tim P., Riley, Richard D., Hattle, Miriam, Papadimitropoulou, Katerina   +4 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

"Moment-Based Estimation of Smooth Transition Regression Models with Endogenous Variables" [PDF]

Nonlinear regression models have been widely used in practice for a variety of time series and cross-section datasets. For purposes of analyzing univariate and multivariate time series data, in particular, Smooth Transition Regression (STR) models have ...
Waldyr Dutra Areosa, Michael McAleer, Marcelo C. Medeiros   +2 more
core   +2 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

New Methods for Two‐Stage Treatment Switching Estimation

Pharmaceutical Statistics
ABSTRACTTreatment switching is common in randomized trials of oncology treatments. For example, control group patients may receive the experimental treatment as a subsequent therapy. One possible estimand is the effect of trial treatment if this type of switching had instead not occurred.
Dan Jackson, Di Ran, Fanni Zhang, Mario Ouwens, Vitaly Druker, Michael Sweeting, Robert Hettle, Ian R. White   +7 more
openaire   +2 more sources

Potential of forest height estimation using X band by means of two different inversion scenarios

, 2007
Polarimetric SAR Interferometry (Pol-InSAR) is a powerful remote sensing method for forest height estimation by using the random volume over ground model (RVoG).
Hajnsek, Irena, Kugler, Florian, Coscia, Angelo, Papathanassiou, Konstantinos   +3 more
core