Results 111 to 120 of about 23,757 (245)

Two-stage strategy for patients with extensive bilateral colorectal liver metastases

open access: yes, 2010
BackgroundTwo-stage hepatectomy has been proposed for patients with bilateral colorectal liver metastases. The present study assesses the feasibility and outcome of two-stage hepatectomy for the treatment of colorectal liver metastases.MethodsFrom ...
Pawlik, Timothy M.   +17 more
core   +1 more source

MiR‐375 in CAFs‐Derived EVs Promotes HCC Progression via Regulating RASA1 and May Potentially Serve as a Biomarker for HCC

open access: yesCancer Science, EarlyView.
CAFs could transfer EVs miR‐375 into endothelial cells with a low level of RASA1 and further promote EC angiogenesis. Plasma EVs miR‐375 have the potential values as a novel diagnostic and prognostic biomarker for HCC. ABSTRACT Cancer‐associated fibroblasts (CAFs) in the tumor microenvironment play an important role in cancer initiation and progression
Wei Qin   +6 more
wiley   +1 more source

Futility and utility of two-stage hepatectomy [PDF]

open access: yesAnnals of Oncology, 2019
M. Cunha   +4 more
openaire   +1 more source

Targeting Egfr‐Mediated Cell Proliferation and Lipid Metabolism Separation Effectively Accelerate Liver Regeneration

open access: yesCell Proliferation, EarlyView.
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu   +7 more
wiley   +1 more source

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

open access: yesCell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo   +5 more
wiley   +1 more source

Advanced lung cancer inflammation index predicts overall survival of hepatocellular carcinoma after hepatectomy

open access: yesFrontiers in Oncology
AimLimited data are available regarding ALI’s clinical relevance and prognostic value in patients with hepatocellular carcinoma (HCC) after hepatectomy.Materials and methodsHCC patients who received hepatectomy at the Meizhou People’s Hospital from May ...
Yuan-Zhang Wen   +5 more
doaj   +1 more source

Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL‐IPSO Survey

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Introduction Surgery is pivotal in the management of hepatoblastoma (HB) although approaches and techniques may vary. The Liver Group of the International Society of Pediatric Oncology (SIOPEL) and the International Pediatric Surgical Oncology (IPSO) group collaborated to develop an online survey to investigate specific technical aspects and ...
Chiara Grimaldi   +9 more
wiley   +1 more source

The emerging role of the Hippo signaling pathway in interorgan crosstalk

open access: yesThe FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song   +2 more
wiley   +1 more source

A review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor?

open access: yes, 2009
Includes bibliographical references (leaves 54-62).Living donor liver transplantation (LDLT) is now well established and performed on a routine basis in many major centres around the world.
Sheriff B Ibirogba, Ibirogba, Sheriff B
core  

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