Results 131 to 140 of about 23,757 (245)

Two-stage hepatectomy in two regional district community hospitals: perioperative safety and long-term survival

, 2017
Introduction - Surgical resection offers the best chance of cure for patients with colorectal liver metastases (CRLMs). Two-stage hepatectomy (TSH) has been demonstrated to be safe and effective to obtain curative resection in patients with multiple ...
Percivale, Andrea, Griseri, Guido, Franceschi, Angelo, Pellicci, Riccardo, SANTORI, GREGORIO, Benasso, Marco, CERIOTTI, MICHELA   +6 more
core   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Mechanistic insights of rapid liver regeneration after associating liver partition and portal vein ligation for stage hepatectomy

, 2016
AIM to highlight the potential mechanisms of regeneration in the Associating Liver Partition and Portal vein ligation for Stage hepatectomy models (clinical and experimental) that could unlock the myth behind the extraordinary capability of the liver for
Vailas, M., Papalampros, A., Vernadakis, S., Dimitrokallis, N., Dimitroulis, D., Petrou, A., Moris, D.   +6 more
core  

Development of an Agent‐Based Model to Investigate Durability of Factor IX Activity in Hemophilia B Patients Treated With Etranacogene Dezaparvovec

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
ABSTRACT Many currently approved gene therapies use adeno‐associated virus (AAV) to deliver DNA sequences encoding protein(s)‐of‐interest into cells. The AAV viral genome forms stable, circular DNA structures called episomes after entering the nuclei. Therapeutic proteins are then generated in vivo from transcription and translation of these episomes ...
Yuezhe Li, Partha Nandy, Eric Jordie, Timothy Knab, Karsten Peppel, Daniel C. Kirouac, A. Katharina Wilkins, Silpa Nuthalapati   +7 more
wiley   +1 more source

ALPPS and conventional two stage hepatectomy in intrahepatic cholangiocarcinoma [PDF]

HPB, 2020
J. Bednarsch, Z. Czigany, I. Amygdalos, D Morales Santana, F. Meister, J. Boecker, U. Neumann, G. Lurje   +7 more
openaire   +1 more source

Changes in urinary taurine and hypotaurine excretion after two-thirds hepatectomy in the rat

, 1998
This study followed the time course of urinary taurine and hypotaurine excretion after two-thirds hepatectomy in rats. The excretion of both taurine and hypotaurine was elevated during 18 h following the hepatectomy, with maximal excretion during the ...
Jörning, G. G., Brand, H. S., Chamuleau, R. A.   +2 more
core   +1 more source

Burnt‐Out MASLD Predicts Outcomes After Curative Resection for Hepatocellular Carcinoma

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Hepatic steatosis often diminishes as metabolic dysfunction–associated steatotic liver disease (MASLD) progresses, leading to a so‐called ‘burnt‐out’ state. Whether this phenotype simply reflects advanced liver injury or represents a biologically distinct condition with prognostic relevance after hepatocellular carcinoma ...
Yukihiro Watanabe, Masayasu Aikawa, Yoshiki Murase, Takuya Oba, Yumiko Kageyama, Kenichiro Takase, Yuichiro Watanabe, Hiroaki Ono, Katsuya Okada, Kojun Okamoto, Isamu Koyama   +10 more
wiley   +1 more source

Investigating the Impact of Carboxylated Polystyrene Nanoplastics in the Liver Using Cell Lines and Precision‐Cut Liver Slices

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Increasing reports of plastic accumulation in human tissue have raised concerns about potential adverse health outcomes. Evidence of negative effects of nanoplastics is heterogeneous and provides limited insights into the underlying pathogenic toxicity mechanisms in humans. Methods In the present study, carboxylate‐modified
Namrata Pandey, Paula Boeira, Nathaniel J. Clark, Eleanor T. Walker, Somaiah Aroori, Jemimah Denson, Richard C. Thompson, Matthew E. Cramp, Shilpa Chokshi, Ashwin Dhanda   +9 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, Volume 13, Issue 35, 24 June 2026.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Synthesis of canine seromucoid before and after total hepatectomy

, 1962
The incorporation rate of S35 DL-methionine into the perchloric acid-soluble (seromucoid) fraction of serum was studied in the same four dogs before and after a one-stage total hepatectomy.
John C. Kukral, Richard J. Winzler, Ronald J. Pancner, June Louch   +3 more
core   +1 more source