Results 121 to 130 of about 23,757 (245)

Spontaneous hepatic tumor regression in an infant with trisomy 18

Pediatric Investigation, EarlyView.
Masashi Hotta, Katsuya Hirata, Shota Inoue, Kohei Higuchi, Eriko Nishi, Kazuko Wada   +5 more
wiley   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Ressecção de metastáses hepáticas em dois estágios e reconstrução da veia cava suprarrenal Two-stage hepatectomy for hepatic metastasis and supra renal vena cava reconstruction

Revista do Colégio Brasileiro de Cirurgiões, 2012
A hepatectomia em duas etapas utiliza a capacidade de regeneração do fígado, após uma primeira hepatectomia não curativa, para permitir uma segunda ressecção.
João Eduardo Nicoluzzi
doaj  

Short chemotherapy-free interval improves oncological outcome in patients undergoing two-stage hepatectomy for colorectal liver metastases

, 2016
BACKGROUND: In patients undergoing two-stage hepatectomy (TSH) for colorectal liver metastases (CRLM), chemotherapy is discontinued before portal vein occlusion and restarted after curative resection.
Raptis, D A, Petrowsky, H, Clavien, P A, Samaras, P, Kambakamba, P, Linecker, M, Alvarez, F A, Reiner, C S, Lesurtel, M, Kron, P, de Santibanes, E   +10 more
core   +1 more source

Evaluating Nurses' Perspectives on the Acceptability and Practicality of Comfort Rounding for Personalised Nutritional and Mobility Care in Surgical Wards: A Mixed‐Methods Feasibility Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To evaluate nurses' perspectives on factors influencing the acceptability and practicality of comfort rounding, focussing on personalised nutritional and mobility care. Design Mixed‐methods feasibility study. Methods Focus group interviews with nurses were conducted before, during and at the end of the implementation period (2022–2023).
Femke Becking‐Verhaar, Fanny Pelzer, Harm Van Noort, Cariline Roosen, Yvonne Van Eijk‐Hustings, Marian De Van Der Schueren, Hester Vermeulen, Getty Huisman‐De Waal   +7 more
wiley   +1 more source

Editorial comment on: surgical outcomes of two-stage hepatectomy for colorectal liver metastasis: comparison to a benchmark procedure. [PDF]

Hepatobiliary Surg Nutr, 2021
Wang Z, Goh BKP.
europepmc   +1 more source

Hyperpolarized MRI Detects Increased [1‐13C]Pyruvate Metabolism in Early Liver Regeneration

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
Hyperpolarized [1‐13C]pyruvate MRI detected increased pyruvate‐to‐lactate and pyruvate‐to‐alanine exchange during early liver regeneration following 70% partial hepatectomy in rats. These findings support the use of hyperpolarized MRI for noninvasive assessment of regenerative metabolism.
Uffe Kjærgaard, Andrea Lund, Lotte Bonde Bertelsen, Esben Søvsø Szocska Hansen, Katrine Holm Andersen, Steffen Ringgaard, Jens Randel Nyengaard, Frank Viborg Mortensen, Christoffer Laustsen   +8 more
wiley   +1 more source

Synchronous Two-Stage Hepatectomy With Associated Liver Partition and Portal Vein Ligation in Addition to Low Anterior Resection for Metastatic Rectal Cancer. [PDF]

Cureus, 2022
Montorfano L, Hutchins S, Bordes SJ, Simpfendorfer CH, Roy M.   +4 more
europepmc   +1 more source

Is Enhanced One-Stage Hepatectomy a Safe and Feasible Alternative to the Two-Stage Hepatectomy in the Setting of Multiple Bilobar Colorectal Liver Metastases? A Comparative Analysis between Two Pioneering Centers

, 2018
<b><i>Background:</i></b> Two-stage hepatectomy (TSH) is the present standard for multiple bilobar colorectal metastases (CLM).
Matteo Donadon, Luca Viganò, Doaa Mansour, Ren Adam, Guido Torzilli, Katsunori Imai, Denis Castaing, Eric Vibert, Matteo Cimino   +8 more
core   +1 more source

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source