Results 121 to 130 of about 341,237 (307)
Time and nodal decomposition with implicit non-anticipativity constraints in dynamic portfolio optimization [PDF]
We propose a decomposition method for the solution of a dynamic portfolio optimization problem which fits the formulation of a multistage stochastic programming problem.
Elio Canestrelli, Diana Barro
core
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Approach for Optimizing 3D Highway Alignments Based on Two-stage Dynamic Programming
Journal of Software, 2013 Optimizing highway alignments is a very complex engineering problem. None of existing methods has totally solved the problem In this paper we build an optimization model for highway 3D alignment based on two-stage dynamic programming, in which the comprehensive cost and design constraints are embedded.
Wei Li 0129 +3 more
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Integrated Optimization of Production Scheduling and Haulage Route Planning in Open-Pit Mines
MathematicsIn mining, deposits are divided into blocks, forming the basis for open-pit mine planning, covering production and haulage route planning. Current studies often stage optimization and lack the consideration of road capacity, leading to suboptimal ...
Changyou Xu +5 more
doaj +1 more source
An interior-point and decomposition approach to multiple stage stochastic programming [PDF]
There is no abstract of this ...
Zhang, S.
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Sparse Antenna Array Design for MIMO Radar Using Multiobjective Differential Evolution
International Journal of Antennas and Propagation, 2016 A two-stage design approach is proposed to address the sparse antenna array design for multiple-input multiple-output radar. In the first stage, the cyclic algorithm (CA) is used to establish a covariance matrix that satisfies the beam pattern ...
Zhi-Kun Chen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source