Results 101 to 110 of about 341,237 (307)
A Multi-Step Sequential System Optimization Design Method for Upper Stages
Journal of Aerospace Technology and Management, 2023 This paper proposes a new approach in multi-step sequential system optimization (MSSO) to implement a conceptual design for satellite upper stage with a maneuver in the conditions close to reality.
Vahid Bohlouri +2 more
doaj
Hybrid GA-SOCP Approach for Placement and Sizing of Distributed Generators in DC Networks
Applied Sciences, 2020 This research addresses the problem of the optimal location and sizing distributed generators (DGs) in direct current (DC) distribution networks from the combinatorial optimization.
Oscar Danilo Montoya +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Quasi-single-stage optimization for permanent magnet stellarators
Nuclear FusionAdvanced stellarators are typically optimized in two stages. The plasma equilibrium is optimized first, followed by the design of coils/permanent magnets.
Guodong Yu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A Two-Stage Optimization Approach for Healthcare Facility Location- Allocation Problems With Service Delivering Based on Genetic Algorithm. [PDF]
Int J Public Health, 2023 Salami A, Afshar-Nadjafi B, Amiri M.
europepmc +1 more source
Multiobjective optimization for multiproduct batch plant design under economic and environmental considerations [PDF]
, 2006 This work deals with the multicriteria cost–environment design of multiproduct batch plants, where the design variables are the size of the equipment items as well as the operating conditions.
Dietz, Adrian +3 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Time-optimal Point-to-point Motion Planning: A Two-stage Approach
IFAC-PapersOnLineThis paper proposes a two-stage approach to formulate the time-optimal point-to-point motion planning problem, involving a first stage with a fixed time grid and a second stage with a variable time grid. The proposed approach brings benefits through its straightforward optimal control problem formulation with a fixed and low number of control steps for
Zhang, Shuhao, Swevers, Jan
openaire +2 more sources