Results 91 to 100 of about 1,020,088 (291)

Hybrid GA-SOCP Approach for Placement and Sizing of Distributed Generators in DC Networks

Applied Sciences, 2020
This research addresses the problem of the optimal location and sizing distributed generators (DGs) in direct current (DC) distribution networks from the combinatorial optimization.
Oscar Danilo Montoya, Walter Gil-González, Luis Fernando Grisales-Noreña   +2 more
doaj   +1 more source

An Aggregated Optimization Model for Multi-Head SMD Placements [PDF]

In this article we propose an aggregate optimization approach by formulating the multi-head SMD placement optimization problem into a mixed integer program (MIP) with the variables based on batches of components.
Ashayeri, J., Ma, N., Sotirov, R.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Optimizing energy flow in advanced microgrids: a prediction-independent two-stage hybrid system approach

Energy Informatics
This paper presents a two-stage optimization framework for long-term energy management in microgrids, aiming to efficiently integrate various energy sources, storage systems, and consumption elements while addressing uncertainties in load demand and ...
Mohamad Javad Mohamadi, Mohammad Tolou Askari, Mahmoud Samiei Moghaddam, Vahid Ghods   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Quasi-single-stage optimization for permanent magnet stellarators

Nuclear Fusion
Advanced stellarators are typically optimized in two stages. The plasma equilibrium is optimized first, followed by the design of coils/permanent magnets.
Guodong Yu, Ke Liu, Tianyi Qian, Yidong Xie, Xianyi Nie, Caoxiang Zhu   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

An optimized two stage U-Net approach for segmentation of pancreas and pancreatic tumor

MethodsX
The segmentation of pancreas and pancreatic tumor remain a persistent challenge for radiologists. Consequently, it is essential to develop automated segmentation methods to address this task.
Himali Ghorpade, Shrikrishna Kolhar, Jayant Jagtap, Jayasree Chakraborty   +3 more
doaj   +1 more source

Approximation Algorithms for Distributionally Robust Stochastic Optimization with Black-Box Distributions

, 2019
Two-stage stochastic optimization is a framework for modeling uncertainty, where we have a probability distribution over possible realizations of the data, called scenarios, and decisions are taken in two stages: we make first-stage decisions knowing ...
Linhares, Andre, Swamy, Chaitanya
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source