Results 71 to 80 of about 1,020,088 (291)

A two-stage approach to enhancing biofuel supply chains through predictive and optimization analytics

Supply Chain Analytics
The escalating pressures of population growth, surging global energy needs, water shortages, reliance on fossil fuels, and urban air pollution underscore the critical demand for sustainable energy alternatives.
Mehdi Soltani Tehrani, Siamak Noori, Ehsan Dehghani   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Application of a Multi-Criterion Decision-Making Method for Solving the Multi-Objective Optimization of a Two-Stage Helical Gearbox

Machines
This paper provides a novel application of a multi-criterion decision-making (MCDM) method to the multi-objective optimization problem of designing a two-stage helical gearbox.
Van-Thanh Dinh, Huu-Danh Tran, Duc-Binh Vu, Duong Vu, Ngoc-Pi Vu, Anh-Tung Luu   +5 more
doaj   +1 more source

Insight into High-quality Aerodynamic Design Spaces through Multi-objective Optimization [PDF]

, 2008
An approach to support the computational aerodynamic design process is presented and demonstrated through the application of a novel multi-objective variant of the Tabu Search optimization algorithm for continuous problems to the aerodynamic design ...
Clarkson, P. J., Dawes, Bill, Jaeggi, Daniel, Kipouros, Timoleon, Parks, Geoff, Savill, Mark A.   +5 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Real-Time Solver For Time-Optimal Control Of Omnidirectional Robots with Bounded Acceleration

, 2018
We are interested in the problem of time-optimal control of omnidirectional robots with bounded acceleration (TOC-ORBA). While there exist approximate solutions for such robots, and exact solutions with unbounded acceleration, exact solvers to the TOC ...
Balaban, David, Biswas, Joydeep, Fischer, Alex   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Improving the Energy Efficiency of the ATAD System through Redesign using Integration Superstructure

Chemical Engineering Transactions, 2018
The aim of this study is application of an approach for solution of two-stage stochastic optimization problem for design of heat-integrated Autothermal Thermophilic Aerobic Digestion (ATAD) bioreactors system for municipal wastewater treatment operating ...
Rayka K. Vladova, Natasha Gr. Vaklieva-Bancheva, Elisaveta G. Kirilova   +2 more
doaj   +1 more source

The clinical target distribution: a probabilistic alternative to the clinical target volume

, 2018
Definition of the clinical target volume (CTV) is one of the weakest links in the radiation therapy chain. In particular, inability to account for uncertainties is a severe limitation in the traditional CTV delineation approach.
Bortfeld, Thomas, Chen, Yen-Lin, Craft, David, Shih, Helen, Shusharina, Nadya   +4 more
core   +1 more source

Identifying Optimal Approaches to Early Termination in Two-Stage Biomarker Validation Studies

Journal of the Royal Statistical Society Series C: Applied Statistics, 2016
SummaryGroup sequential study designs have been proposed as an approach to conserve resources in biomarker validation studies. Typically, group sequential study designs allow both ‘early termination to reject the null hypothesis’ and ‘early termination for futility’ if there is evidence against the alternative hypothesis.
Kaizer, Alexander M., Koopmeiners, Joseph S.   +1 more
openaire   +2 more sources