Results 81 to 90 of about 1,020,088 (291)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
On three soft rectangle packing problems with guillotine constraints
, 2018 We investigate how to partition a rectangular region of length $L_1$ and height $L_2$ into $n$ rectangles of given areas $(a_1, \dots, a_n)$ using two-stage guillotine cuts, so as to minimize either (i) the sum of the perimeters, (ii) the largest ...
Bui, Quoc Trung +2 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Nonlinear Analysis, 2019 This paper presents a Bayesian approach rooted algorithm oriented to the properties of multi-objective optimization problems. The performance of the developed algorithm is compared with several other multi-objective optimization algorithms.
Antanas Žilinskas +3 more
doaj +3 more sources
, 2019 Cross-view image translation is challenging because it involves images with drastically different views and severe deformation. In this paper, we propose a novel approach named Multi-Channel Attention SelectionGAN (SelectionGAN) that makes it possible to
Corso, Jason J. +5 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A Multi-Step Sequential System Optimization Design Method for Upper Stages
Journal of Aerospace Technology and Management, 2023 This paper proposes a new approach in multi-step sequential system optimization (MSSO) to implement a conceptual design for satellite upper stage with a maneuver in the conditions close to reality.
Vahid Bohlouri +2 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Two‐Stage Energy‐Efficiency Optimization Approach for Conflict‐Free Dispatching in Open‐Pit Mines
IET Intelligent Transport SystemsThe objective of this paper is to present a novel energy‐efficiency conflict‐free dispatching algorithm for autonomous mining fleets. In lieu of halting or decelerating the trucks at intersections when conflicts arise, the algorithm facilitates conflict ...
Zhichao Wang +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source