Results 71 to 80 of about 746,046 (294)

A two-stage stochastic programming with recourse model for determining robust planting plans in horticulture [PDF]

, 2000
A two-stage stochastic programming with recourse model for the problem of determining optimal planting plans for a vegetable crop is presented in this paper.
Audsley, E, Barker, S, Darby-Dowman, K, Parsons, D   +3 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Large-Scale Convex Optimization for Dense Wireless Cooperative Networks

, 2015
Convex optimization is a powerful tool for resource allocation and signal processing in wireless networks. As the network density is expected to drastically increase in order to accommodate the exponentially growing mobile data traffic, performance ...
Letaief, Khaled B., O'Donoghue, Brendan, Shi, Yuanming, Zhang, Jun   +3 more
core   +2 more sources

Approach for Optimizing 3D Highway Alignments Based on Two-stage Dynamic Programming

Journal of Software, 2013
Optimizing highway alignments is a very complex engineering problem. None of existing methods has totally solved the problem In this paper we build an optimization model for highway 3D alignment based on two-stage dynamic programming, in which the comprehensive cost and design constraints are embedded.
Wei Li, Hao Pu, Haifeng Zhao, Wei Liu
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Multi-project scheduling with 2-stage decomposition [PDF]

, 2010
A non-preemptive, zero time lag multi-project scheduling problem with multiple modes and limited renewable and nonrenewable resources is considered. A 2-stage decomposition approach is adopted to formulate the problem as a hierarchy of 0-1 mathematical ...
Can, Anıl, Can, Anil, Ulusoy, Gunduz, Ulusoy, Gündüz   +3 more
core  

A two-stage stochastic integer programming approach

, 2005
This research has been partially support by the grant Grupo consolidado de alto rendimiento 9/UPV 00038.321-13631/2001 from UPV, the project MEC2001-0636 from the DGCIT, the Researchers’ Education grant program 2000 from Gobierno Vasco, and the grant GRUPOS79/04 from the Generalitat Valenciana, Spain.
Merino Maestre, María, Pérez Sainz de Rozas, Gloria, Escudero Bueno, Laureano F., Garín Martín, María Araceli   +3 more
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cooperative two-stage network dea: a goal programming approach

, 2019
In this study, we present a two-stage data envelopment analysis method dealing with efficiency evaluation of decision making units with network structure. The key point of the study is that the suggested model optimizes the Black-Box and stages efficiencies simultaneously with the aim of achieving the smallest possible gap between the aspiration levels.
ZAHİRİ, P., MİRBOLOUKİ, M.
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source