Results 41 to 50 of about 103,048 (257)

Shape-memory behavior of cross-linked semi-crystalline polymers and their blends

eXPRESS Polymer Letters, 2015
The present study deals with thermally induced one-way and invertible two-way shape-memory effect (SME) in covalent networks on the basis of crystallizable (co)polymers and their blends and is an attempt to generalize the results of own investigation ...
I. Kolesov, O. Dolynchuk, H.-J. Radusch
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A study of two-way shape memory effect in CuZnAL aLloy

Journal de Physique III, 1991
A new comparatively convenient training program for two-way shape memory effect (TWSME) in CuZnAl alloy was introduced. The internal friction, frequency, zero point shift of torsion pendulum and electric resistance were synchronistically measured during TWSME cycle.
He, Jia-Jie, Huang, Yuan-Ti, Cheng, Hua-Qi   +2 more
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Role of Nickel Content in One-Way and Two-Way Shape Recovery in Binary Ti-Ni Alloys

Metals, 2021
The shape recovery characteristics of titanium nickelide with an Ni content of 50.0 at % and 50.7 at % were studied in a wide range of structures obtained as a result of cold drawing with an accumulated true strain of e = 0.52 and subsequent annealing in
Elena P. Ryklina, Kristina A. Polyakova, Sergey D. Prokoshkin   +2 more
doaj   +1 more source

Intrinsic two-way shape memory effect in a Ni-Mn-Sn metamagnetic shape memory microwire

Journal of Materials Science & Technology, 2020
Abstract An intrinsic two-way shape memory effect with a fully recoverable strain of 1.0 % was achieved in an as-prepared Ni50Mn37.5Sn12.5 metamagnetic shape memory microwire fabricated by Taylor-Ulitovsky method. This two-way shape memory effect is mainly owing to the internal stress caused by the retained martensite in austenite matrix, as revealed
Zhen Chen, Daoyong Cong, Yin Zhang, Xiaoming Sun, Runguang Li, Shaohui Li, Zhi Yang, Chao Song, Yuxian Cao, Yang Ren, Yandong Wang   +10 more
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

4D printing of semi-crystalline crosslinked polymer networks with two-way shape-memory effect

Materials & Design
This paper introduces a novel approach to 4D printing tailored structures with reversible two-way shape-memory effect (SME) through material extrusion technology.
Lorenzo Bonetti, Daniele Natali, Stefano Pandini, Massimo Messori, Maurizio Toselli, Giulia Scalet   +5 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source