Results 91 to 100 of about 21,525 (213)

Cutting Edge: FimH Adhesin of Type 1 Fimbriae Is a Novel TLR4 Ligand [PDF]

The Journal of Immunology, 2008
Abstract Several TLR ligands of bacterial origin induce innate immune responses. Although FimH, the adhesin portion of type 1 fimbria, plays an important role in the pathogenicity of some Gram-negative bacteria, its ability to stimulate the innate immune system via TLR signaling remains unclear.
Karen L, Mossman, M Firoz, Mian, Nicole M, Lauzon, Carlton L, Gyles, Brian, Lichty, Randy, Mackenzie, Navkiran, Gill, Ali A, Ashkar   +7 more
openaire   +2 more sources

La régulation des fimbriae de type 1 chez les Escherichia coli uropathogènes

, 2021
Les E. coli pathogènes extra-intestinaux (ExPEC) sont responsables d'un large éventail d'infections invasives chez l'homme et les animaux. Les E. coli uropathogènes (UPEC) sont le principal agent étiologique des infections du tractus urinaire (ITU ...
Bessaiah, Hicham
core  

Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder Epithelial Cells

Frontiers in Cellular and Infection Microbiology, 2018
The NLRP3 inflammasome and IL-1β release have recently been suggested to be important for the progression of urinary tract infection (UTI). However, much is still unknown regarding the interaction of UPEC and the NLRP3 inflammasome.
Isak Demirel, Isak Demirel, Alexander Persson, Alexander Persson, Annelie Brauner, Eva Särndahl, Eva Särndahl, Robert Kruse, Robert Kruse, Robert Kruse, Katarina Persson, Katarina Persson   +11 more
doaj   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Molecular Basis for the Enterocyte Tropism Exhibited bySalmonella typhimurium Type 1 Fimbriae [PDF]

Journal of Biological Chemistry, 1999
Salmonella typhimurium exhibits a distinct tropism for mouse enterocytes that is linked to their expression of type 1 fimbriae. The distinct binding traits of Salmonella type 1 fimbriae is also reflected in their binding to selected mannosylated proteins and in their ability to promote secondary bacterial aggregation on enterocyte surfaces.
K, Thankavel, A H, Shah, M S, Cohen, T, Ikeda, R G, Lorenz, R, Curtiss, S N, Abraham   +6 more
openaire   +2 more sources

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Analysis of Escherichia coli strains causing bacteriuria during pregnancy: selection for strains that do not express type 1 fimbriae

, 2001
Escherichia coli isolates from patients with bacteriuria of pregnancy were compared by PCR with isolates from patients with community-acquired cystitis for the presence of established virulence determinants.
Graham, J.C., Keegan, S J, Bint, A, Pearson, J, Leathart, J B, Gally, David   +5 more
core  

Structural and mechanical properties of klebsiella pneumoniae type 3 fimbriae

, 2011
[[abstract]]This study investigated the structural and mechanical properties of Klebsiella pneumoniae type 3 fimbriae, which constitute a known virulence factor for the bacterium.
Ying-Jung Huang, Kuo-Liang Liu, Hwei-Ling Peng, Chen, FJ;Chan, CH;Huang, YJ;Liu, KL;Peng, HL;Chang, HY;Liou, GG;Yew, TR;Liu, CH;Hsu, KY;Hsu, L, Feng-Jung Chen, Ken Y. Hsu, Chia-Han Chan, Hwan-You Chang, Tri-Rung Yew, Long Hsu, Gunn-Guang Liou, Cheng-Hsien Liu   +11 more
core   +1 more source

Diverse Microbial Communities Assemble on Both Recalcitrant and Labile Carbon Sources

Environmental Microbiology, Volume 28, Issue 7, July 2026.
Taxonomically and functionally distinct communities assemble on cellulose and its monomer, glucose. Although single carbon sources were provided, high and comparable diversity was maintained in both environments, supported by extensive cross‐feeding and scavenging. However, glucose supported higher biomass than cellulose and selected generalists, while
Kaumudi H. Prabhakara, Yansong Zhao, Kristian Ullrich, Andrew D. Farr, Paul B. Rainey   +4 more
wiley   +1 more source

Using Stock Vulnerability to Evaluate Fishery‐Independent Survey Coverage and Inform Sampling Priorities

Fish and Fisheries, Volume 27, Issue 4, Page 912-926, July 2026.
ABSTRACT The consequences of mis‐managing vulnerable stocks (i.e., those with low productivity and high susceptibility to depletion) are high and potentially permanent. To support sustainable fisheries management, stock assessments can be improved by increasing the quantity and quality of fishery‐independent survey (i.e., survey) data.
Derek G. Bolser, Lewis A. K. Barnett, Jason Cope   +2 more
wiley   +1 more source