Results 201 to 210 of about 4,423,584 (309)

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

open access: yesAdvanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma   +9 more
wiley   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

A Smart and Highly Porous Hydrogel for Diabetic Wound Healing

open access: yesAdvanced Materials Interfaces, EarlyView.
A novel hydrogel comprising a dual‐crosslinked network of Poly(N‐isopropylacrylamide) (PNIPAM) and Gum Arabic (GA) with superior mechanical and anti‐inflammatory properties is designed for advanced diabetic wound healing. Abstract Conventional hydrogels often suffer from poor mechanical strength, limited bioactivity, and uncontrolled therapeutic ...
Nouf Al Saleh   +9 more
wiley   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao   +6 more
wiley   +1 more source

Flow Analysis in Pathological Microvascular Models by Ultrasound Localization Microscopy

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a new platform combining ultrasound localization microscopy with biomimetic gelatin phantoms to analyze flow dynamics in small vessels with narrowing or obstructions. Using microbubble tracking, the method enables high‐resolution velocity mapping in 100–500 µm channels, revealing flow changes in pathological microvascular conditions
Yarin Gershman   +3 more
wiley   +1 more source

Management of dyslipidaemia in patients with comorbidities-facing the challenge: type 1 diabetes mellitus. [PDF]

open access: yesEur Heart J Cardiovasc Pharmacother
Kaser S   +5 more
europepmc   +1 more source

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