Results 261 to 270 of about 36,666,975 (299)
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Autoantibodies in Type 1 diabetes
Diabetes Research and Clinical Practice, 2010Type 1 diabetes is an autoimmune disease manifested by an autoimmune attack on the pancreatic beta-islet cells. It is also known that Type 1 diabetes is associated with other autoimmune diseases. The aim of the present study was to seek autoantibodies in the serum of people with Type 1 diabetes.
Panagiotis, Heras +7 more
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Microchimerism in type 1 diabetes
Current Diabetes Reports, 2009The observation that maternal cells can transfer from mother to child during pregnancy and differentiate into many different tissues including islet beta cells is exciting and intriguing, and to date has generated more questions than answers: Could these genetically distinct maternal cells play a role in the initiation of autoimmune diabetes in the ...
vanZyl, B, Gillespie, KM
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The geoepidemiology of type 1 diabetes
Autoimmunity Reviews, 2010Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by absolute insulin deficiency resulting from the progressive immune-mediated destruction of pancreatic islet beta cells. It is thought to be triggered by as yet unidentified environmental factors in genetically susceptible individuals, the major genetic contribution coming from loci ...
Andrea T, Borchers +2 more
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Nursing Clinics of North America, 2017
Comprehensive type 1 diabetes management requires understanding of the pathophysiology of disease and the ability to contrast this process with type 2 diabetes. Nurses are often the first contact with patients and must be aware of the advancements in detection, therapies, and signs of complications in these patients.
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Comprehensive type 1 diabetes management requires understanding of the pathophysiology of disease and the ability to contrast this process with type 2 diabetes. Nurses are often the first contact with patients and must be aware of the advancements in detection, therapies, and signs of complications in these patients.
openaire +2 more sources
Cell Biochemistry and Biophysics, 2007
At the time of this writing, a major void exists; the lack of a method to prevent and/or reverse type 1 diabetes in humans. We believe this void to a large extent is the result of our lack in understanding the mechanisms of autoimmunity that underlie beta cell destruction, a failure to understand the immunologic factors that contribute to type 1 ...
Todd, Brusko, Mark, Atkinson
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At the time of this writing, a major void exists; the lack of a method to prevent and/or reverse type 1 diabetes in humans. We believe this void to a large extent is the result of our lack in understanding the mechanisms of autoimmunity that underlie beta cell destruction, a failure to understand the immunologic factors that contribute to type 1 ...
Todd, Brusko, Mark, Atkinson
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Primary Care: Clinics in Office Practice, 2007
Although less prevalent than type 2 diabetes, autoimmune type 1 diabetes presents numerous challenges, including many that must be addressed daily. Patients must have appropriate tools to confront and manage their physiologic insulin deficiency syndrome.
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Although less prevalent than type 2 diabetes, autoimmune type 1 diabetes presents numerous challenges, including many that must be addressed daily. Patients must have appropriate tools to confront and manage their physiologic insulin deficiency syndrome.
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Endocrinology and Metabolism Clinics of North America, 2010
This article reviews economic methodologies developed for estimating cost of illness, examines the current literature on diabetes costs, and presents the latest estimates of the economic impact of type 1 diabetes in terms of direct medical costs (ie, treatment costs) and indirect costs (eg, lost wages).
Betty T, Tao, David G, Taylor
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This article reviews economic methodologies developed for estimating cost of illness, examines the current literature on diabetes costs, and presents the latest estimates of the economic impact of type 1 diabetes in terms of direct medical costs (ie, treatment costs) and indirect costs (eg, lost wages).
Betty T, Tao, David G, Taylor
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2012
Type 1 diabetes has a strong genetic component but additional environmental factors have also an essential role. This is demonstrated by the multifold rise in incidence of the disease during the last decades in most industrialized countries. The most important genes are located within the HLA region, where class II genes largely define the disease risk.
Hermann, Robert, Ilonen, Jorma
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Type 1 diabetes has a strong genetic component but additional environmental factors have also an essential role. This is demonstrated by the multifold rise in incidence of the disease during the last decades in most industrialized countries. The most important genes are located within the HLA region, where class II genes largely define the disease risk.
Hermann, Robert, Ilonen, Jorma
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The Foundation Years, 2002
Abstract Failure of the thyroid gland requires thyroid hormone replacement therapy, which is relatively easily adjusted to replicate the normal physiological state by monitoring plasma levels of thyroxine and/or thyroid-stimulating hormone. In contrast, failure of pancreatic b-cells requires insulin therapy, and optimal replacement requires monitoring,
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Abstract Failure of the thyroid gland requires thyroid hormone replacement therapy, which is relatively easily adjusted to replicate the normal physiological state by monitoring plasma levels of thyroxine and/or thyroid-stimulating hormone. In contrast, failure of pancreatic b-cells requires insulin therapy, and optimal replacement requires monitoring,
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Medical Clinics of North America, 1998
This article discusses type 1 diabetes mellitus, which results from insulin deficiency caused by autoimmune destruction of the insulin-producing beta-cells in the pancreatic islets of Langerhans. The autoimmune response against islet beta-cells is believed to result from a disorder of immunoregulation. According to this concept, T lymphocytes (T cells)
A, Rabinovitch, J S, Skyler
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This article discusses type 1 diabetes mellitus, which results from insulin deficiency caused by autoimmune destruction of the insulin-producing beta-cells in the pancreatic islets of Langerhans. The autoimmune response against islet beta-cells is believed to result from a disorder of immunoregulation. According to this concept, T lymphocytes (T cells)
A, Rabinovitch, J S, Skyler
openaire +2 more sources