Results 291 to 300 of about 2,183,210 (336)

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source

The Use of Continuous Glucose Monitoring to Diagnose Stage 2 Type 1 Diabetes. [PDF]

J Diabetes Sci Technol
Mader JK, Wong JC, Freckmann G, Garcia-Tirado J, Hirsch IB, Johnson SB, Kerr D, Kim SH, Lal R, Montaser E, O'Donnell H, Pleus S, Shah VN, Ayers AT, Ho CN, Biester T, Dovc K, Farrokhi F, Fleming A, Gillard P, Heinemann L, López-Díez R, Maahs DM, Mathieu C, Quandt Z, Rami-Merhar B, Wolf W, Klonoff DC.   +27 more
europepmc   +1 more source

Self‐Maintainable Electronic Materials with Skin‐Like Characteristics Enabled by Graphene‐PEDOT:PSS Fillers

Advanced Science, EarlyView.
Graphene‐PEDOT:PSS fillers revolutionize soft electronics by transforming jelly‐like materials into skin‐like systems with self‐healing, heat‐responsiveness, and multiplex sensing capabilities. This novel material exhibits exceptional printability, flexibility, and adhesiveness, enabling seamless integration into bioelectronics and tissue‐cyborganic ...
Morteza Alehosseini, Firoz Babu Kadumudi, Sinziana Revesz, Parham Karimi Reikandeh, Jonas Rosager Henriksen, Tiberiu‐Gabriel Zsurzsan, Jon Spangenberg, Alireza Dolatshahi‐Pirouz   +7 more
wiley   +1 more source

Immunomodulatory agents and cell therapy for patients with type 1 diabetes. [PDF]

Arch Endocrinol Metab
Rodacki M, Silva KR, Araujo DB, Dantas JR, Ramos MEN, Zajdenverg L, Baptista LS.   +6 more
europepmc   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Nutritional experiences of Turkish university students with type 1 diabetes: a qualitative study. [PDF]

J Health Popul Nutr
Özgen Özkaya Ş, Özkaya V, Gedıklı E, Garıpağaoğlu M.   +3 more
europepmc   +1 more source

A Bead‐Based Quantum Dot Immunoassay Integrated with Multi‐Module Microfluidics Enables Real‐Time Multiplexed Detection of Blood Insulin and Glucagon

Advanced Science, EarlyView.
The quantum dot integrated real‐time ELISA or QIRT‐ELISA system integrates a bead‐based quantum dot‐mediated immunoassay (BQI) with a modular microfluidic system to continuously monitor insulin and glucagon in whole blood samples and in a multiplexed setting.
Hesam Abouali, Sanjana Srikant, Md Fahim Al Fattah, Nicole G. Barra, Darryl Chan, Dayan Ban, Jonathan D. Schertzer, Mahla Poudineh   +7 more
wiley   +1 more source

New Perspectives in Studying Type 1 Diabetes Susceptibility Biomarkers. [PDF]

Int J Mol Sci
Park Y, Ko KS, Rhee BD.
europepmc   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Type 1 Diabetes TrialNet: Leading the Charge in Disease Prediction, Prevention, and Immunotherapeutic Mechanistic Understanding. [PDF]

Diabetes Care
Jacobsen LM, Felton JL, Nathan BM, Speake C, Krischer J, Herold KC.   +5 more
europepmc   +1 more source