Diabetes mellitus tipo 1: multifatores que conferem suscetibilidade à patogenia auto-imune = Type 1 diabetes mellitus: multifactors that confer susceptibility to the autoimmune pathogenesis [PDF]
, 2007 Objetivos: revisar dados de literatura concernentes aos fatores que conferem suscetibilidade à patogenia auto-imune do diabetes mellitus tipo 1. Fonte de dados: revisão de artigos especializados no assunto publicados em bancos de dados nacionais e ...
Saitovich, David +2 more
core
Advanced Healthcare Materials, EarlyView.This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam +7 more
wiley +1 more source
A meta-analysis of rate ratios for nocturnal confirmed hypoglycaemia with insulin degludec vs. insulin glargine using different definitions for hypoglycaemia [PDF]
, 2016 Aims: A prospective meta-analysis of phase 3 trials showed lower rates of nocturnal hypoglycaemia with insulin degludec vs. insulin glargine. We investigated the consistency of the results across different definitions of hypoglycaemia.
Bode +20 more
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Celiac disease in type 1 diabetes mellitus [PDF]
Italian Journal of Pediatrics, 2012 Abstract Celiac Disease (CD) occurs in patients with Type 1 Diabetes (T1D) ranging the prevalence of 4.4-11.1% versus 0.5% of the general population. The mechanism of association of these two diseases involves a shared genetic background: HLA genotype DR3-DQ2 and DR4-DQ8 are strongly associated with T1D, DR3-DQ2 with CD.
Maria Erminia Camarca +10 more
openaire +4 more sources
Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun +9 more
wiley +1 more source
Alteration in CD8+ T cell subsets in enterovirus-infected patients: An alarming factor for type 1 diabetes mellitus [PDF]
, 2018 Type 1 diabetes is a multi-factorial disease that can develop due to the combination of genetic and environmental factors. Viruses, particularly enteroviruses, are major environmental candidates in the pathogenesis of type 1 diabetes, even though the ...
Ghatrehsamani, Mahdi +9 more
core +4 more sources
Immigration, myocardial infarction, and type 1 diabetes in Sweden : use of the migration and health cohort [PDF]
, 2014 The aim of this study was to examine the risks for and time trends of first-time myocardial infarction and type 1 diabetes mellitus, and the equity of admission to specialized care and evidence-based treatments after first-time myocardial infarction in ...
Yang, Dong
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Enteroviruses and type 1 diabetes mellitus
Biomedicine & Pharmacotherapy, 2003 Despite decades of research, the etiology of type 1 diabetes mellitus (DM) is unknown. Several risk factors have been associated with type 1 DM, including viral infections, genetic predisposition, nutritional factors, and chemicals. Several investigators hypothesize that the etiologies of type 1 DM result from a complex interaction of genetic and ...
Harry W. Haverkos +3 more
openaire +3 more sources
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
Advanced Healthcare Materials, EarlyView.This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source
Struggling towards diagnosis: Experiences of Iranian diabetes [PDF]
, 2014 Background: Healthcare-seeking behavior is one of the factors determining the uptake and outcome of healthcare. However, few studies have discussed how and why diabetics seek healthcare assistance before meeting a physician. Objectives: In this study, we
Arshadi Bostanabad, M. +4 more
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