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Rapid evolution of Klebsiella pneumoniae biofilms in vitro delineates adaptive changes selected during infection. [PDF]
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Role of type 1 fimbriae in EPEC infections
Microbial Pathogenesis, 1997Several fimbriae have been implicated as potentially important in EPEC adhesion and pathogenesis. EPEC strain E2348/69 produced only bundle forming pili and type 1 fimbriae, and did not produce other accesory adhesins identified in EPEC strain B171. Cloning and mutagenesis of these EPEC fim genes indicated that type 1 pili had no affect on levels or ...
Simon J Elliott, James B Kaper
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Actinomyces Adsorption Mediated by Type-1 Fimbriae
Journal of Dental Research, 1986Monospecific antibody against the type-1 fimbriae of Actinomyces viscosus T14V reacted with 12 strains of A. viscosus (serotype 2), 12 strains of A. naeslundii (serotype 2 or serotype 3), but not with 11 serotype 1 strains of A. naeslundii. All strains positive for the type-1 fimbrial antigen adsorbed strongly to saliva-treated hydroxyapatite, and in ...
W B, Clark +3 more
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Structure, Function, and Assembly of Type 1 Fimbriae
2009Bacterial infections constitute a major global health problem, acutely accentuated by the rapid spread of antibiotic resistant bacterial strains. The widespread need for bacteria to attach - adhere - to target cells before they can initiate an infection may be used to advantage by targeting the bacterial adhesion tools such as pili and fimbriae for ...
Stefan D, Knight, Julie, Bouckaert
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Production of type 1 fimbriae by Escherichia coli HB101
Microbial Pathogenesis, 1991Escherichia coli HB101 is frequently used as a host in the cloning of bacterial virulence genes because of its reported lack of virulence determinants such as fimbriae, adhesins and haemagglutinins. However, passage of HB101 in standing broth culture rapidly induced the production of fimbriae which mediated adhesion to HEp-2 cells and mannose-sensitive
S J, Elliott, N, Nandapalan, B J, Chang
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Functional Variability of Type 1 Fimbriae of Escherichia coli
2005Type 1 fimbriae and the FimH-adhesins of E. coli differ in adhesive functions: those of a meningitis isolate IHE3034 mediate adhesion to collagens whereas those of an avirulent K-12 strain PC31 do not. Amino acid residue Alanine-62 in the FimH is critical for the collagen binding ability: substitution of Ala62 of IHE3034 FimH into serine abolishes ...
R, Pouttu +7 more
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Type 1 fimbriae of Escherichia coli as carriers of heterologous antigenic sequences
Gene, 1989A strategy has been designed for the construction of recombinant bacterial strains which eventually may become useful as live vaccines and which may also be relevant for the preparation of conventional vaccines. The approach used is the fusion of small antigenic peptide sequences into specific segments of a protein whose location on the bacterial ...
L, Hedegaard, P, Klemm
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FimK regulation on the expression of type 1 fimbriae in Klebsiella pneumoniae CG43S3
Microbiology, 2013Klebsiella pneumoniae CG43, a heavy encapsulated liver abscess isolate, mainly expresses type 3 fimbriae. Type 1 fimbriae expression was only apparent in CG43S3ΔmrkA (the type 3 fimbriae-deficient strain). The expression of type 1 fimbriae in CG43S3ΔmrkA was reduced by deleting the fimK gene, but was unaffected by removing the 3' end of fimK encoding ...
Zhe-Chong, Wang +4 more
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