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The Lancet, 2017
415 million people live with diabetes worldwide, and an estimated 193 million people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients with diabetes and leads to microvascular and macrovascular complications that cause profound psychological and physical distress to both patients and carers and put a huge burden on ...
Sudesna, Chatterjee +2 more
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415 million people live with diabetes worldwide, and an estimated 193 million people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients with diabetes and leads to microvascular and macrovascular complications that cause profound psychological and physical distress to both patients and carers and put a huge burden on ...
Sudesna, Chatterjee +2 more
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Annals of Internal Medicine, 2010
Type 2 diabetes is a prevalent illness that causes major vascular, renal, and neurologic complications. Prevention and treatment of diabetes and its complications are of paramount importance. Many new treatments have emerged over the past 5-10 years. Recent evidence shows that newer treatments may substantially reduce risk for cardiac and renal disease,
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Type 2 diabetes is a prevalent illness that causes major vascular, renal, and neurologic complications. Prevention and treatment of diabetes and its complications are of paramount importance. Many new treatments have emerged over the past 5-10 years. Recent evidence shows that newer treatments may substantially reduce risk for cardiac and renal disease,
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Drugs of Today, 2022
Type 2 diabetes mellitus is a chronic disease most often characterized by increased glucose levels. When blood glucose levels are inadequately controlled or left untreated, the result is a variety of microvascular and macrovascular complications. To prevent these outcomes, many medications are available to manage type 2 diabetes mellitus and prevent ...
Jessica, Huston +9 more
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Type 2 diabetes mellitus is a chronic disease most often characterized by increased glucose levels. When blood glucose levels are inadequately controlled or left untreated, the result is a variety of microvascular and macrovascular complications. To prevent these outcomes, many medications are available to manage type 2 diabetes mellitus and prevent ...
Jessica, Huston +9 more
openaire +2 more sources
Type 2 Diabetes and Bacteremia
Annals of Nutrition and Metabolism, 2017Background: A high proportion of type 2 diabetes cases are associated with host genetic and environmental factors. During the past decade, microorganisms that inhabit the gut have emerged as contributors to the pathogenesis of obesity and type 2 diabetes.
Junko, Sato +2 more
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The Nurse Practitioner, 2013
Ms. P is a 50-year-old, Black female diagnosed with type 2 diabetes after presenting to her primary care provider with polyuria, polydipsia, and blurry vision. She had a fasting blood glucose (BG) level of 204 mg/dL and a hemoglobin A1c (HbA1C) level of 7.8%. At this visit, Ms.
Stacey, Seggelke, Bridget, Everhart
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Ms. P is a 50-year-old, Black female diagnosed with type 2 diabetes after presenting to her primary care provider with polyuria, polydipsia, and blurry vision. She had a fasting blood glucose (BG) level of 204 mg/dL and a hemoglobin A1c (HbA1C) level of 7.8%. At this visit, Ms.
Stacey, Seggelke, Bridget, Everhart
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Current Problems in Pediatric and Adolescent Health Care, 2004
r s a t e e a l D a p t b c Amid reports identifying obesity as one of the ost significant public health problems in the nited States comes the comprehensive review f type 2 diabetes in youth in this month’s Current roblems in Pediatrics. The authors, Dr. Lenna iu and colleagues, point out that for most peditricians, we last received training on type 2
Lenna, Liu +2 more
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r s a t e e a l D a p t b c Amid reports identifying obesity as one of the ost significant public health problems in the nited States comes the comprehensive review f type 2 diabetes in youth in this month’s Current roblems in Pediatrics. The authors, Dr. Lenna iu and colleagues, point out that for most peditricians, we last received training on type 2
Lenna, Liu +2 more
openaire +2 more sources
Annals of the New York Academy of Sciences, 2004
Abstract:Carnitine, the l‐β‐hydroxy‐γ‐N‐trimethylaminobutyric acid, is synthesized primarily in the liver and kidneys from lysine and methionine. Carnitine covers an important role in lipid metabolism, acting as an obligatory cofactor for β‐oxidation of fatty acids by facilitating the transport of long‐chain fatty acids across the mitochondrial ...
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Abstract:Carnitine, the l‐β‐hydroxy‐γ‐N‐trimethylaminobutyric acid, is synthesized primarily in the liver and kidneys from lysine and methionine. Carnitine covers an important role in lipid metabolism, acting as an obligatory cofactor for β‐oxidation of fatty acids by facilitating the transport of long‐chain fatty acids across the mitochondrial ...
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Gluconeogenesis in Type 2 Diabetes
1993There is now considerable evidence that increased hepatic glucose output rather than reduced peripheral glucose uptake is the primary factor responsible for both fasting and postprandial hyperglycemia in type 2 diabetes1,2. It is, therefore, appropriate to consider the mechanisms that may be involved in permitting and promoting this excessive hepatic ...
J E, Gerich, N, Nurjhan
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2011
The evolving concept of how nutrient excess and inflammation modulate metabolism provides new opportunities for strategies to correct the detrimental health consequences of obesity. In this review, we focus on the complex interplay among lipid overload, immune response, proinflammatory pathways and organelle dysfunction through which excess adiposity ...
Christina, Schwanstecher +1 more
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The evolving concept of how nutrient excess and inflammation modulate metabolism provides new opportunities for strategies to correct the detrimental health consequences of obesity. In this review, we focus on the complex interplay among lipid overload, immune response, proinflammatory pathways and organelle dysfunction through which excess adiposity ...
Christina, Schwanstecher +1 more
openaire +2 more sources
Endocrinology and Metabolism Clinics of North America, 2019
Hyperglycemia is common during pregnancy, involving multisystem adaptations. Pregnancy-induced metabolic changes increase insulin resistance. Pregnancy-induced insulin resistance adds to preexisting insulin resistance. Preexisting pancreatic β-cell defect compromises the ability to enhance insulin secretion, leading to hyperglycemia.
Kapur, Anil +2 more
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Hyperglycemia is common during pregnancy, involving multisystem adaptations. Pregnancy-induced metabolic changes increase insulin resistance. Pregnancy-induced insulin resistance adds to preexisting insulin resistance. Preexisting pancreatic β-cell defect compromises the ability to enhance insulin secretion, leading to hyperglycemia.
Kapur, Anil +2 more
openaire +5 more sources